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Sarcomatoid Renal Cell Carcinoma Metastasis to the Penis
Victor D Liou1, Oussama M Darwish2, Mary M Henry3
1Saint Louis University School of Medicine, Saint Louis, MO 63104, USA.
Abstract:
Secondary cancers of the penis are extremely uncommon with less than 300 cases reported in the past 100 years. These cancers are most frequently a result of an aggressive or poorly managed primary prostate or bladder cancer and rarely a metastasis from a primary kidney tumor. Currently, there is no published literature which describes the spread of sarcomatoid renal cell carcinoma (SRCC) to the penis. In this report, we present a 55-year-old-man who presented with a large right-sided SRCC which metastasized to the base of his penis within 1 month of symptom onset. We also discuss the possible route of metastasis based on primary tumor size and location within the retroperitoneum.
Insights
Secondary penile cancers are rare, with sarcomatoid renal cell carcinoma (SRCC) metastasis to the penis being undocumented. This case report details a patient with SRCC who developed penile metastasis rapidly, highlighting a novel pathway for cancer spread.
Area of Science:
- Urology
- Oncology
- Pathology
Background:
- Secondary penile cancers are exceptionally rare, with fewer than 300 cases documented historically.
- Metastasis to the penis typically originates from prostate or bladder cancers; kidney cancer metastasis is uncommon.
- No prior literature describes sarcomatoid renal cell carcinoma (SRCC) spreading to the penis.
Purpose of the Study:
- To report the first documented case of penile metastasis from sarcomatoid renal cell carcinoma (SRCC).
- To discuss the potential metastatic pathway of SRCC to the penis.
- To contribute to the understanding of rare cancer dissemination patterns.
Main Methods:
- Case presentation of a 55-year-old male patient.
- Clinical evaluation of a large right-sided SRCC.
- Documentation of rapid metastasis to the penile base.
Main Results:
- A 55-year-old man presented with a large right-sided SRCC.
- Penile metastasis at the base occurred within one month of symptom onset.
- This represents the first reported instance of SRCC metastasizing to the penis.
Conclusions:
- Sarcomatoid renal cell carcinoma (SRCC) can metastasize to the penis, a previously unreported phenomenon.
- Tumor size and retroperitoneal location may influence the route of penile metastasis.
- This finding expands the known spectrum of SRCC metastatic behavior.