Related Experiment Video
Updated: Apr 5, 2026

Detection of Invasive Pulmonary Aspergillosis in Haematological Malignancy Patients by using Lateral-flow Technology
Published on: March 22, 2012
Central Nervous System Aspergilloma in an Immunocompetent Patient: A Case Report
Hasanreza Mohammadi1, Sohrab Sadeghi1, Shokrollah Zandi2
1Dept. of Neurosurgery, Imam Hossein Hospital, Shahid Beheshti University of Medical Sciences (SBMU), Tehran, Iran.
Abstract:
Intracranial aspergilloma is extremely rare. The diagnosis and treatment of invasive CNS aspergillosis is very difficult. Early diagnosis is important for a successful treatment. Here, we report a case of intracranial aspergilloma in an 11-year-old boy in 2013. Good outcome was achieved by treatment with a combination of neurosurgical resection and antifungal administration, which we suggest is a good quality management plan.
Insights
Intracranial aspergilloma, a rare fungal infection of the brain, requires early diagnosis. Successful treatment involves neurosurgical resection and antifungal medication for a good outcome.
Area of Science:
- Neurology
- Infectious Diseases
- Mycology
Background:
- Intracranial aspergilloma is an exceptionally rare fungal infection affecting the central nervous system (CNS).
- Diagnosis and management of invasive CNS aspergillosis present significant challenges.
- Prompt diagnosis is critical for effective therapeutic interventions and improved patient prognosis.
Purpose of the Study:
- To report a rare case of intracranial aspergilloma in a pediatric patient.
- To highlight the diagnostic and therapeutic strategies employed.
- To propose a management plan for successful treatment.
Main Methods:
- Case report of an 11-year-old boy diagnosed with intracranial aspergilloma in 2013.
- Treatment involved a combination of surgical resection and antifungal therapy.
- Clinical outcome was assessed post-intervention.
Main Results:
- The patient achieved a favorable outcome following the combined treatment approach.
- The integrated management strategy proved effective in resolving the intracranial aspergilloma.
- This case demonstrates the feasibility of successful intervention in rare CNS fungal infections.
Conclusions:
- A combined approach of neurosurgical resection and antifungal administration is a viable and effective management plan for intracranial aspergilloma.
- Early diagnosis and prompt, aggressive treatment are essential for achieving good outcomes in CNS aspergillosis.
- This case underscores the importance of multidisciplinary care in managing rare neurological infections.
More Related Videos
09:52Histological Quantification to Determine Lung Fungal Burden in Experimental Aspergillosis
Published on: March 9, 2018
15:01Confocal Laser Scanning Microscopy-Based Quantitative Analysis of Aspergillus fumigatus Conidia Distribution in Whole-Mount Optically Cleared Mouse Lung
Published on: September 18, 2021
Related Concept Videos
Fungal Phylum Ascomycota
Pneumonia I: Introduction
Risk Factors
Various factors influence the likelihood of developing pneumonia. Age plays a crucial role, with infants, children under two, and individuals over 65 at increased risk due to their...