[Liver damage caused by HIV infection]

Hepatic status was studied in 7 HIV-infected patients at the stage of generalized lymphadenopathy. Intravital needle biopsy obtained from the livers characterizes the latter as enlarged, showing signs of protein-synthesis dysfunction, morphological evidence of mild cytolysis, cholestasis, moderate mesenchymal-inflammatory syndrome. The study of autopsy specimens obtained from hepatic tissue of the woman who had died of AIDS disclosed more advanced lesions: hepatocytes dystrophy, intralobular and periportal infiltration. The conclusion is made on the necessity of liver function examination entailing due therapeutic measures when following up patients with HIV infection and AIDS.