Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Osteoclasts in Bone Remodeling01:31

Osteoclasts in Bone Remodeling

4.8K
Osteoclasts are cells responsible for bone resorption and remodeling. They originate from hematopoietic progenitor cells present in the bone marrow. Numerous progenitor cells fuse to form multinucleated cells, each with 10-20 nuclei. A single osteoclast has a diameter of 150 to 200 µM. These cells have ruffled borders that break down the underlying bone tissue and release minerals such as calcium into the blood in bone resorption. Osteoclasts cling to bones with their ruffled edges during...
4.8K
Bone Disorders01:29

Bone Disorders

8.0K
Aging and its effect on bone remodeling is the most common cause of bone disorders. In young and healthy people, bone deposition and resorption happen at an equal rate to maintain optimal bone health.
Bone deposition is also affected by the levels of sex hormones like estrogen and testosterone that promote osteoblast activity and bone matrix synthesis. When the level of these hormones decreases due to aging, it causes a reduction in bone deposition. As a result, bone resorption by osteoclasts...
8.0K
Essential Minerals for Bone Health01:31

Essential Minerals for Bone Health

7.2K
The minerals contained in all of the food we consume are essential for our organ systems. However, certain essential minerals, such as calcium, phosphorus, magnesium, manganese, and fluoride, largely affect bone health.
Calcium and Phosphorus
Calcium is a critical component of bones, especially in the form of calcium phosphate and calcium carbonate. Since the body cannot make calcium, it must be obtained from the diet. However, calcium cannot be absorbed from the small intestine without...
7.2K
Bone Remodeling01:40

Bone Remodeling

41.1K
Bone remodeling is a continuous and balanced process of bone resorption by osteoclasts and bone formation by osteoblasts. In adults, it helps maintain bone mass and calcium homeostasis. While mechanical stress can stimulate turnover as part of the normal maintenance and reparative process, several hormones also regulate bone remodeling.
41.1K
Urinary Tract Calculi IV: Nutrition Therapy and Prevention01:27

Urinary Tract Calculi IV: Nutrition Therapy and Prevention

660
Management of renal calculi focuses on effective strategies like tailored nutrition and hydration therapy. Adjusting diet and fluid intake reduces stone formation and recurrence, making these interventions simple yet powerful in kidney stone prevention and management.Understanding Kidney StonesKidney stones form when calcium, oxalate, uric acid, and cystine concentrate and crystallize in urine. Factors contributing to their formation include genetic predisposition, certain medical conditions,...
660
Role of Vitamins in Maintaining Bone Health01:25

Role of Vitamins in Maintaining Bone Health

6.0K
The growth and maintenance of bone are regulated by a combination of nutritional factors, including vitamins, such as vitamin A, B12, C, D, and K.
Vitamin A
Vitamin A is involved in the process of bone remodeling. Retinoic acid, the active metabolite of Vitamin A, has nuclear receptors in osteoblasts and osteoclasts, which are involved in bone remodeling.
Vitamin B12
Vitamin B12 acts as a cofactor during the formation of osteoblast-related proteins, such as osteocalcin. Vitamin B12 plays a role...
6.0K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Healthcare waste: from incineration to pyrolysis: a comparative life cycle assessment of two different healthcare plastic waste management processes.

BMC health services research·2026
Same author

Report of high data rate macromolecular crystallography (HDRMX) meeting, 23 July 2025.

Structural dynamics (Melville, N.Y.)·2026
Same author

Clonal hematopoiesis of indeterminate potential in high grade B-cell lymphomas: clinicobiological associations and further insight with single-cell multiomics analysis.

Blood cancer journal·2026
Same author

Erratum: Real-world outcomes in spinal cord stimulation: predictors of reported effect and explantation using a comprehensive registry-based approach: Erratum.

Pain reports·2026
Same author

Evaluating work activity and societal burden in patients with grade 2 IDH-mutant glioma.

Neuro-oncology practice·2026
Same author

Autoantibody repertoire analysis in paraneoplastic pemphigus reveals novel targets linked to mucocutaneous blistering and bronchiolitis obliterans.

Communications medicine·2026

Related Experiment Video

Updated: Apr 5, 2026

Semiautomated Longitudinal Microcomputed Tomography-based Quantitative Structural Analysis of a Nude Rat Osteoporosis-related Vertebral Fracture Model
07:12

Semiautomated Longitudinal Microcomputed Tomography-based Quantitative Structural Analysis of a Nude Rat Osteoporosis-related Vertebral Fracture Model

Published on: September 28, 2017

8.7K

Swedish osteoporosis care.

Emma Jonsson1, Daniel Eriksson, Kristina Åkesson

  • 1Quantify Research, Hantverkargatan 8, 112 21, Stockholm, Sweden.

Archives of Osteoporosis
|August 12, 2015
PubMed
Summary

Swedish osteoporosis care faces challenges in identifying high-risk patients and ensuring secondary fracture prevention. Treatment rates and adherence are low, particularly for men and older women, necessitating improved care strategies.

More Related Videos

Author Spotlight: Exploring the Impact of Lingnan Fire-Needle Therapy in Osteoporosis Intervention
03:56

Author Spotlight: Exploring the Impact of Lingnan Fire-Needle Therapy in Osteoporosis Intervention

Published on: April 26, 2024

1.4K

Related Experiment Videos

Last Updated: Apr 5, 2026

Semiautomated Longitudinal Microcomputed Tomography-based Quantitative Structural Analysis of a Nude Rat Osteoporosis-related Vertebral Fracture Model
07:12

Semiautomated Longitudinal Microcomputed Tomography-based Quantitative Structural Analysis of a Nude Rat Osteoporosis-related Vertebral Fracture Model

Published on: September 28, 2017

8.7K
Author Spotlight: Exploring the Impact of Lingnan Fire-Needle Therapy in Osteoporosis Intervention
03:56

Author Spotlight: Exploring the Impact of Lingnan Fire-Needle Therapy in Osteoporosis Intervention

Published on: April 26, 2024

1.4K

Area of Science:

  • Public Health
  • Health Services Research
  • Gerontology

Background:

  • Osteoporosis poses a significant disease burden in Sweden.
  • Current care pathways struggle with identifying high-risk individuals and providing secondary fracture prevention.
  • Existing care is characterized by fragmented patient management and low treatment rates.

Purpose of the Study:

  • To review and describe the current state of Swedish osteoporosis care.
  • To identify gaps and challenges in osteoporosis management and secondary fracture prevention.
  • To develop quality and process measures for comparing regional care variations.

Main Methods:

  • Analysis of Swedish national registry data for quantitative health outcomes.
  • Surveys and interviews with healthcare representatives.
  • Development and application of quality and process measures for care evaluation.

Main Results:

  • Low treatment rates (3-16%) observed post-fracture, with disparities between genders and age groups.
  • Limited treatment adherence and high rates of patient non-persistence.
  • Significant regional variations in care quality and a lack of interdisciplinary collaboration.

Conclusions:

  • Swedish osteoporosis care requires significant improvement in patient identification, treatment initiation, and adherence.
  • Enhanced collaboration and standardized secondary prevention programs are crucial.
  • The study provides a basis for future evaluations and regional improvements in osteoporosis care.