Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

In Vitro Fertilization01:24

In Vitro Fertilization

1.4K
In vitro fertilization (IVF) is a form of assisted reproductive technology where an egg is fertilized with sperm in a controlled laboratory environment before transferring the resulting embryo into the uterus. This process is designed to help individuals and couples experiencing difficulties conceiving.
The IVF process begins with ovarian stimulation, during which reproductive endocrinologists prescribe hormonal medications to stimulate the ovaries to produce multiple eggs instead of the single...
1.4K
Meiosis II01:57

Meiosis II

210.7K
Meiosis II is the second and final stage of meiosis. It relies on the haploid cells produced during meiosis I, each of which contain only 23 chromosomes—one from each homologous initial pair. Importantly, each chromosome in these cells is composed of two joined copies, and when these cells enter meiosis II, the goal is to separate such sister chromatids using the same microtubule-based network employed in other division processes. The result of meiosis II is two haploid cells, each...
210.7K
Infertility in Females01:28

Infertility in Females

5.0K
Female infertility is defined as the inability to conceive after a year of regular, unprotected intercourse and affects about 10–15% of couples worldwide. The primary cause of female infertility is ovulatory disorders, which hinder the release of eggs. These disorders can be classified as hypothalamic amenorrhea, polycystic ovarian syndrome (PCOS), premature ovarian failure, and hyperprolactinemic anovulation disorders.
Endometriosis, a condition characterized by abnormal growth of...
5.0K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Ovarian reserve markers in World Health Organization type 1 anovulatory disorders: a systematic review and meta-analysis.

Reproductive biomedicine online·2026
Same author

Validation of an HPLC-MS method for simultaneous determination of seven troponin activators in human urine and serum for doping control.

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences·2026
Same author

Reducing pain and anxiety with virtual reality in (outpatient) gynecological procedures: a systematic review with meta-analysis.

AJOG global reports·2026
Same author

Cost-effectiveness of time-lapse monitoring with or without the use of embryo selection software compared to routine incubation and selection.

Human reproduction open·2026
Same author

Reproductive outcomes after fertility preservation using tamoxifen or letrozole in women with breast cancer: a long-term follow-up.

F&S reports·2026
Same author

Systematic review and meta-analysis of information source usage: do medical specialists use the best evidence for clinical decision-making?

BMJ open·2026

Related Experiment Video

Updated: Apr 5, 2026

OP-IVM: Combining In vitro Maturation after Oocyte Retrieval with Gynecological Surgery
05:31

OP-IVM: Combining In vitro Maturation after Oocyte Retrieval with Gynecological Surgery

Published on: May 9, 2021

5.0K

Minimal stimulation IVF vs conventional IVF: a randomized controlled trial.

John J Zhang1, Zaher Merhi2, Mingxue Yang1

  • 1Department of Reproductive Endocrinology and Infertility, New Hope Fertility Center, New York, NY.

American Journal of Obstetrics and Gynecology
|August 12, 2015
PubMed
Summary
This summary is machine-generated.

Minimal stimulation in vitro fertilization (mini-IVF) offers reduced risks like OHSS and multiple pregnancies compared to conventional IVF. However, mini-IVF resulted in lower live birth rates in this trial.

Keywords:
IVFOHSSclomiphene citratemini-IVFmultiple pregnancy

More Related Videos

Fertility Preservation Through Oocyte Vitrification: Clinical and Laboratory Perspectives
08:46

Fertility Preservation Through Oocyte Vitrification: Clinical and Laboratory Perspectives

Published on: September 16, 2021

6.9K
Author Spotlight: Evaluating the Impact of Immediate Partial Removal of Cumulus-Oocyte Complexes on Fertilization Efficiency and Embryo Quality
08:06

Author Spotlight: Evaluating the Impact of Immediate Partial Removal of Cumulus-Oocyte Complexes on Fertilization Efficiency and Embryo Quality

Published on: October 18, 2024

1.0K

Related Experiment Videos

Last Updated: Apr 5, 2026

OP-IVM: Combining In vitro Maturation after Oocyte Retrieval with Gynecological Surgery
05:31

OP-IVM: Combining In vitro Maturation after Oocyte Retrieval with Gynecological Surgery

Published on: May 9, 2021

5.0K
Fertility Preservation Through Oocyte Vitrification: Clinical and Laboratory Perspectives
08:46

Fertility Preservation Through Oocyte Vitrification: Clinical and Laboratory Perspectives

Published on: September 16, 2021

6.9K
Author Spotlight: Evaluating the Impact of Immediate Partial Removal of Cumulus-Oocyte Complexes on Fertilization Efficiency and Embryo Quality
08:06

Author Spotlight: Evaluating the Impact of Immediate Partial Removal of Cumulus-Oocyte Complexes on Fertilization Efficiency and Embryo Quality

Published on: October 18, 2024

1.0K

Area of Science:

  • Reproductive Medicine
  • In Vitro Fertilization

Background:

  • Minimal stimulation in vitro fertilization (mini-IVF) is an alternative protocol designed to decrease risks associated with conventional IVF.
  • Potential benefits include reduced ovarian hyperstimulation syndrome (OHSS), lower multiple pregnancy rates, and decreased costs.
  • It aims to maintain high live birth rates.

Purpose of the Study:

  • To compare the efficacy and safety of mini-IVF with single embryo transfer against conventional IVF with double embryo transfer.
  • The study was designed as a randomized noninferiority controlled trial with a 10% noninferiority margin.

Main Methods:

  • A randomized controlled trial involving 564 infertile women under 39 undergoing their first IVF cycle.
  • Participants were randomized to either mini-IVF or conventional IVF.
  • The primary outcome was the cumulative live birth rate over 6 months, with secondary outcomes including OHSS, multiple pregnancies, and gonadotropin use.

Main Results:

  • Mini-IVF resulted in a cumulative live birth rate of 49% compared to 63% for conventional IVF.
  • No cases of OHSS were observed with mini-IVF, versus 5.7% in the conventional IVF group.
  • Multiple pregnancy rates were significantly lower in the mini-IVF group (6.4% vs. 32%), with substantially reduced gonadotropin consumption.

Conclusions:

  • Mini-IVF with single embryo transfer significantly reduces OHSS and multiple pregnancy rates compared to conventional IVF with double embryo transfer.
  • While effective in reducing certain risks and costs, mini-IVF demonstrated lower live birth rates in this study.
  • Further research may explore optimizing mini-IVF protocols to improve live birth outcomes.