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Concomitant tuberculosis and lung cancer diagnosed by bronchoscopy
C Morales-García1, J Parra-Ruiz2, J A Sánchez-Martínez3
1Department of Pulmonology, Virgen de las Nieves University Hospital, Granada, Spain.
Summary
Concomitant tuberculosis (TB) and lung cancer diagnoses were identified in 15 cases. Early screening for TB in lung cancer patients, especially in high-prevalence areas, is recommended.
Area of Science:
- Pulmonology
- Oncology
- Infectious Diseases
Background:
- Tuberculosis (TB) and lung cancer can co-occur.
- Screening programs aim to detect diseases early.
Purpose of the Study:
- To characterize cases of concurrent tuberculosis and lung cancer.
- To evaluate the incidence of TB and lung cancer co-diagnosis.
Main Methods:
- A descriptive study analyzed 319 TB cases from January 2003 to December 2010 in the South Granada Health Area (SGHA).
- Bronchial secretion samples were collected during fiberoptic bronchoscopy (FBS) as part of TB screening.
Main Results:
- Concomitant TB and lung cancer were diagnosed in 15 cases (4.7% of TB cases).
- Atelectasis was the most frequent radiographic finding (53.3%).
- Epidermoid carcinoma (60%) was the most common histology, with 60% of cases at advanced stages (III-IV).
Conclusions:
- The SGHA TB screening program identified a higher rate of TB and lung cancer association than previously reported.
- Recommends acid-fast bacilli smear and mycobacterial culture of bronchial aspirates for all presumed lung cancer patients, particularly in high TB prevalence regions.
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