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Related Concept Videos

Genomics02:02

Genomics

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Genomics is the science of genomes: it is the study of all the genetic material of an organism. In humans, the genome consists of information carried in 23 pairs of chromosomes in the nucleus, as well as mitochondrial DNA. In genomics, both coding and non-coding DNA is sequenced and analyzed. Genomics allows a better understanding of all living things, their evolution, and their diversity. It has a myriad of uses: for example, to build phylogenetic trees, to improve productivity and...
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Genome Size and the Evolution of New Genes03:21

Genome Size and the Evolution of New Genes

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Genome Size and the Evolution of New Genes03:21

Genome Size and the Evolution of New Genes

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While every living organism has a genome of some kind (be it RNA, or DNA), there is considerable variation in the sizes of these blueprints. One major factor that impacts genome size is whether the organism is prokaryotic or eukaryotic. In prokaryotes, the genome contains little to no non-coding sequence, such that genes are tightly clustered in groups or operons sequentially along the chromosome. Conversely, the genes in eukaryotes are punctuated by long stretches of non-coding sequence.
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Genomic DNA in Eukaryotes00:58

Genomic DNA in Eukaryotes

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Eukaryotes have large genomes compared to prokaryotes. To fit their genomes into a cell, eukaryotic DNA is packaged extraordinarily tightly inside the nucleus. To achieve this, DNA is tightly wound around proteins called histones, which are packaged into nucleosomes that are joined by linker DNA and coil into chromatin fibers. Additional fibrous proteins further compact the chromatin, which is recognizable as chromosomes during certain phases of cell division.
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Next-generation Sequencing03:00

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The first human genome sequencing project cost $2.7 billion and was declared complete in 2003, after 15 years of international cooperation and collaboration between several research teams and funding agencies. Today, with the advent of next-generation sequencing technologies, the cost and time of sequencing a human genome have dropped over 100 fold.
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Genetic Screens02:46

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Genetic screens are tools used to identify genes and mutations responsible for phenotypes of interest. Genetic screens help identify individuals or a group of people at risk of developing  genetic diseases and help them with early intervention, targeted therapy, and reproductive options.
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Related Experiment Video

Updated: Apr 5, 2026

Using Human Differentially Expressed Gene Lists to Perform Downstream Pathway Enrichment Analysis and Target Prioritization
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Genomic Resources Notes accepted 1 April 2015 - 31 May 2015.

, Vera Maria Fonseca Almeida-Val1, E Boscari2

  • 1Laboratório de Ecofisiologia e Evolução Molecular, Instituto Nacional de Pesquisas da Amazônia (INPA), Av. André Araújo 2.936, Petrópolis, CEP 69067-375 Manaus, AM, 2223, Brazil.

Molecular Ecology Resources
|August 12, 2015
PubMed
Summary

Publicly available transcriptomic data for stellate sturgeon, Campanula gentilis, and two Iberian fish (Squalius carolitertii, Squalius torgalensis) are now accessible. These resources support biodiversity and conservation research.

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Area of Science:

  • Genomics
  • Bioinformatics
  • Conservation Biology

Background:

  • Transcriptomic data are crucial for understanding gene expression and evolutionary processes.
  • Limited genomic resources exist for several understudied aquatic and plant species.

Purpose of the Study:

  • To document the public release of novel transcriptomic datasets.
  • To provide foundational genomic information for Acipenser stellatus, Campanula gentilis, Squalius carolitertii, and Squalius torgalensis.

Main Methods:

  • Transcriptome sequencing and assembly.
  • Data archiving in public repositories.

Main Results:

  • Generated and validated transcriptomic resources for four distinct species.
  • Ensured accessibility of these valuable datasets for the scientific community.

Conclusions:

  • The public availability of these transcriptomic datasets significantly enhances research capabilities in ichthyology, botany, and evolutionary studies.
  • These resources will aid in future conservation efforts and biological research for these species.