Related Experiment Video
Updated: Apr 5, 2026

Pharmacophore Modeling for Targets with Extensive Ligand Libraries: A Case Study on SARS-CoV-2 Mpro
Published on: September 26, 2025
Let's 'play' with molecular pharmacology.
Supriyo Choudhury, Richeek Pradhan, Gairik Sengupta
1Department of Pharmacology, Institute of Post Graduate Medical Education and Research, Kolkata, West Bengal, India.
Role-play effectively enhances undergraduate medical students' understanding of molecular pharmacology. This active learning method significantly improves knowledge retention and is highly accepted by students.
Area of Science:
- Medical Education
- Pharmacology
- Active Learning Strategies
Background:
- Molecular mechanisms of drug action are complex for undergraduates.
- Role-play facilitates visualization and active participation in teaching physiology.
- The efficacy of role-play in molecular pharmacology education is underexplored.
Purpose of the Study:
- To investigate the effectiveness of role-play in teaching molecular pharmacology.
- To assess student acceptance of role-play as a teaching method.
Main Methods:
- An observational study guided students through a role-play on drug activity.
- Knowledge gain was measured using pre- and post-test questionnaires and normalized gain.
- Student acceptance was evaluated via Likert scales and thematic analysis of written feedback.
Main Results:
- Significant knowledge improvement was observed (P < 0.001).
- High class average normalized gain indicated effective learning.
- 93% of students found role-play an acceptable teaching method, with identified strengths and weaknesses.
Conclusions:
- Role-play is an effective and well-accepted teaching tool for molecular pharmacology.
- It can be successfully integrated into undergraduate medical curricula.
More Related Videos
07:45A Manual Small Molecule Screen Approaching High-throughput Using Zebrafish Embryos
Published on: November 8, 2014
13:18Network Pharmacology Prediction and Experimental Validation of Trichosanthes-Fritillaria thunbergii Action Mechanism Against Lung Adenocarcinoma
Published on: March 3, 2023
Related Concept Videos
Pharmacodynamics: Overview and Principles
Most drugs' effects result from their interactions with drug receptors or targets within the body. These interactions trigger specific responses at the cellular or systemic level. Drug receptors can be found on the surfaces of cells or...
Pharmacogenetics and Pharmacogenomics: Overview
Pharmacogenetic Phenotypes: Alterations in Pharmacokinetics, Drug Targets and Biologic Milieu
Pharmacogenomics: Identification of New Drug Targets
Pharmacogenetics of Drug Metabolism: Overview
Principles of Pharmacogenetics: Types of Genetic Variants