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Disseminated cutaneous phaeohyphomycosis due to Cladophialophora bantiana
Anza Khader1, Betsy Ambooken, Manikoth Payyanadan Binitha
1Department of Dermatology and Venereology, Govt Medical College, Kozhikode, India.
Abstract:
Cladophialophora bantiana is a neurotropic dematiaceous fungus which only rarely affects the skin. We report a case of disseminated cutaneous phaeohyphomycosis caused by Cladophialophora bantiana in an immunocompromised female who presented with multiple pyogenic granuloma-like nodules, dermatophytosis-like plaque, and subcutaneous cysts on the upper and lower extremities without systemic involvement. Biopsy revealed black yeasts resembling sclerotic bodies and culture yielded irregular, velvety, grey colonies with black reverse. Excision of the nodules and treatment with oral itraconazole 100 mg twice daily resulted in complete clinical resolution within two months, following which itraconazole was administered for another 4 months.
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