The Systemic Control of Growth
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Updated: Apr 5, 2026

The Use of Chemostats in Microbial Systems Biology
Published on: October 14, 2013
Laura Boulan1, Marco Milán2, Pierre Léopold1
1University of Nice-Sophia Antipolis, 06108 Nice, France CNRS, University of Nice-Sophia Antipolis, 06108 Nice, France INSERM, University of Nice-Sophia Antipolis, 06108 Nice, France.
Abstract:
Growth is a complex process that is intimately linked to the developmental program to form adults with proper size and proportions. Genetics is an important determinant of growth, as exemplified by the role of local diffusible molecules setting up organ proportions. In addition, organisms use adaptive responses allowing modulating the size of individuals according to environmental cues, for example, nutrition. Here, we describe some of the physiological principles participating in the determination of final individual size.
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