Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Bilateral experimental myopia in chicks.

J G Sivak1, D L Barrie, J A Weerheim

  • 1School of Optometry, University of Waterloo, Ontario, Canada.

Optometry and Vision Science : Official Publication of the American Academy of Optometry
|December 1, 1989
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Optical performance of the bovine lens before and after cold cataract.

Applied optics·2010
Same author

Dose-response of the cultured bovine lens to butyl, methyl and propyl parabens.

International journal of cosmetic science·2008
Same author

The effects of toxicological agents on the optics and mitochondria of the lens and the mitochondria of the corneal epithelium.

Seminars in cell & developmental biology·2007
Same author

Optical function and mitochondrial metabolic properties in damage and recovery of bovine lens after in vitro carbonyl cyanide m-chlorophenylhydrazone treatment.

Mitochondrion·2005
Same author

Optical quality changes of the ocular lens during induced parr-to-smolt metamorphosis in Rainbow Trout (Oncorhynchus mykiss). Ocular lens optical quality during induced salmonid metamorphosis.

Journal of comparative physiology. A, Neuroethology, sensory, neural, and behavioral physiology·2005
Same author

Long-term lens organ culture system with a method for monitoring lens optical quality.

Photochemistry and photobiology·2005

Bilateral visual deprivation in chicks induces myopia. Surprisingly, the eye with partial visual blur becomes significantly more myopic than the other eye, suggesting complex neural control of refractive development.

Area of Science:

  • Ophthalmology
  • Developmental Biology
  • Neuroscience

Background:

  • Myopia induction is achievable through visual deprivation in young animals.
  • Previous studies predominantly utilized unilateral visual deprivation models.
  • Understanding refractive development is crucial for addressing myopia prevalence.

Purpose of the Study:

  • To investigate the effects of bilateral visual deprivation on refractive development in chicks.
  • To compare the myopic effects of unilateral versus bilateral visual deprivation.
  • To explore the influence of varying visual deprivation levels on refractive error.

Main Methods:

  • Chicks were subjected to 2 weeks of post-hatching visual deprivation.
  • One eye was covered with an opaque goggle, the other with a translucent goggle.

Related Experiment Videos

  • Refractive states and lens focal characteristics were assessed.
  • Main Results:

    • Bilateral visual deprivation induced myopia in both eyes.
    • The eye under the translucent goggle exhibited greater myopia compared to the opaque-deprived eye.
    • Lens focal characteristics remained unaffected by the induced myopia.
    • Deprivation of one eye influenced the refractive development of the contralateral eye.

    Conclusions:

    • Partial visual blur during development can lead to more significant myopia than complete deprivation.
    • Contralateral eye effects suggest non-local neural mechanisms in refractive control.
    • Findings have implications for understanding central versus peripheral neural control of eye growth and refractive development.