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Non Functional Unilateral Adrenal Myelolipoma, A Case Report
Anita B Sajjanar1, Vidisha S Athanikar2, U S Dinesh2
1Assistant Professor, Department of Pathology, SDM College of Medical Sciences & Hospital , Dharwad, Karnataka, India .
Journal of Clinical and Diagnostic Research : JCDR
|August 13, 2015
Summary
Adrenal myelolipoma, a benign adrenal tumor with fat and bone marrow, is often found incidentally. This case highlights a large, non-functional adrenal myelolipoma diagnosed via imaging and confirmed by histopathology.
Area of Science:
- Endocrinology
- Oncology
- Pathology
Background:
- Adrenal myelolipomas are rare, benign tumors composed of mature adipose tissue and hematopoietic elements.
- Most adrenal myelolipomas are non-functional and discovered incidentally during imaging or autopsy.
- Occasionally, these tumors can grow large enough to cause symptoms or be detected as abdominal masses.
Observation:
- A 58-year-old female presented with a palpable abdominal mass.
- Preoperative imaging (computer tomography scan) and laboratory tests indicated a non-functional adrenal myelolipoma.
- Gross examination revealed a unilateral ovoid mass with a capsule, fat, and congested areas.
Findings:
- Microscopic examination confirmed a well-encapsulated tumor.
- The tumor consisted of mature adipose tissue and active bone marrow elements, including myeloid, erythroid, and megakaryocytic series.
- Histopathological examination of the adrenalectomy specimen definitively diagnosed adrenal myelolipoma.
Implications:
- This case underscores the importance of histopathological confirmation for adrenal myelolipoma diagnosis.
- Understanding the composition of adrenal myelolipoma is crucial for differentiating it from other adrenal neoplasms.
- Surgical resection (adrenalectomy) may be indicated for symptomatic or large adrenal myelolipomas.
