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Updated: Apr 5, 2026

RNAscope for In situ Detection of Transcriptionally Active Human Papillomavirus in Head and Neck Squamous Cell Carcinoma
Published on: March 11, 2014
Human Papilloma Virus (HPV) Induced Head & Neck Squamous Cell Carcinoma: A Comprehensive Retrospect
Roquaiya Nishat1, Shyam Sundar Behura2, Sujatha Ramachandra2
1Post Graduate Student, Department of Oral Pathology and Microbiology, Kalinga Institute of Dental Sciences , KIIT University, Bhubaneswar, Odisha, India .
Abstract:
Head and Neck Squamous Cell Carcinoma accounts for the sixth most common malignancy occurring worldwide with tobacco and alcohol being the two well established risk factors. In the recent years, substantial evidence has been obtained that Human Papilloma Virus (HPV) associated head and neck cancers are on the rise. This article provides an insight into the structure of HPV genome, molecular pathogenesis, detection methods and clinical implications of HPV positive Head and Neck Squamous Cell Carcinoma.
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