[Relationship between the ischemic ST-T changes in ECG and the coronary artery diseases]
Wei Huang1, Mingshi Yang1, Xuehui Xiao1
1Department of Emergency, Third Xiangya Hospital, Central South University, Changsha 410013, China.
Insights
Electrocardiogram (ECG) ST-T changes are valuable for diagnosing coronary artery disease. While ECG shows higher sensitivity for myocardial ischemia in women, it offers greater specificity in men.
Area of Science:
- Cardiology
- Diagnostic Imaging
Background:
- Coronary artery disease (CAD) diagnosis relies on various methods.
- Electrocardiogram (ECG) ST-T wave changes can indicate myocardial ischemia.
Purpose of the Study:
- To evaluate the diagnostic utility of ischemic ST-T changes on ECG for coronary artery disease.
- To compare the diagnostic performance between sexes.
Main Methods:
- 341 patients undergoing coronary angiography were analyzed.
- Standard diagnostic criteria for ischemic ST-T changes and coronary angiography were used.
- Sensitivity and specificity of ECG for diagnosing CAD were calculated.
Main Results:
- Ischemic ST-T changes were more prevalent in women (P<0.01).
- Overall ECG sensitivity was 83.6% and specificity was 54.4%.
- Sex-specific analysis revealed higher sensitivity in women (85.0%) and higher specificity in men (68.0%).
Conclusions:
- Ischemic ST-T changes on ECG are significant for diagnosing coronary artery disease.
- ECG demonstrates differential diagnostic performance between sexes for myocardial ischemia.
Objective:
To analyze the relationship between the ischemic ST-T changes in electrocardiogram (ECG) and the coronary artery diseases based on the perspective of diagnostics.
Methods:
A total of 341 patients, who underwent coronary angiography in Department of Cardiology of Xiangya Hospital, Central South University from June 2013 to April 2014, were enrolled for this study. The internationally recognized diagnostic criteria for ischemic ST-T changes in ECG and the Judkins diagnostic criteria for coronary angiography were applied, respectively. The sensitivity and specificity of ECG were analyzed.
Results:
There were more ischemic ST-T changes in women than that in men (P<0.01). Ischemic changes in coronary angiography were not significantly different between male and female patients (P>0.05). For ischemic diagnostic tests by ECG ST-T, the total sensitivity and specificity was 83.6% and 54.4%, respectively. The sensitivity and specificity was 82.3% and 68.0% or 85.0% and 28.2% in the male or female group, respectively.
Conclusion:
Ischemic ST-T changes in ECG possess important value in the diagnosis of the coronary artery diseases. The sensitivity of ECG in the diagnosis of myocardial ischemia in women was higher than that in men, whereas the specificity of ECG in the diagnosis of myocardial ischemia in men was higher than that in women.
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