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Updated: Apr 5, 2026

Comparative Proteomic Analysis of Whole Kidney, Medulla, and Cortical Tubules in Diabetic Pathogenesis of Kidney Injury in Mice
Published on: May 2, 2025
URINARY LOSS OF MICRONUTRIENTS IN DIABETIC PATIENTS ATTENDING A TERTIARY HOSPITAL SERVICE
Andressa Feijó da Silva Santos1, Roberta Deh Souza Santos1, Maria Cristina Foss-Freitas1
1Departament of Internal Medicine, Faculty of Medicine of Ribeirão Preto, Ribeirao Preto, São Paulo (Brazil).. andressa_feijo@yahoo.com.br.
Background/Aims:
micronutrient deficiency may contribute to a poorer control of diabetes. Thus, the objective of the present study was to assess the urinary excretion of micronutrients in patients with type 2 diabetes mellitus.
Methods:
patients with diabetes and controls were assessed regarding food intake, anthropometry, urinary loss of micronutrients and compared by the nonparametric Mann-Whitney test (p < 0.05).
Results:
nine diabetic volunteers (52 ± 14 years, BMI 30 ± 11 kg/m² and abdominal circumference (AC) of 99 ± 25 cm) and 9 control individuals (51 ± 16 years, BMI 26 ± 5 kg/m² and AC of 90 ± 13 cm) were studied. Higher iron excretion was observed in the diabetic group and higher magnesium excretion in the control group.
Conclusions:
the type 2 diabetic patients here studied did not show increased micronutrient excretion in urine when compared to controls.
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