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Updated: Apr 5, 2026

Author Spotlight: Exploring the Impact of Reduced Resistance Exercise Volume on Metabolic Health
Published on: December 1, 2023
POSITIVE EFFECTS OF RESISTANCE TRAINING ON INFLAMMATORY PARAMETERS IN MEN WITH METABOLIC SYNDROME RISK FACTORS
Mariane Silveira Martins1, Juliano Boufleur Farinha2, Chane Basso Benetti3
1Federal University of Santa Maria, Santa Maria, RS.. mari_silveira_martins@yahoo.com.br.
Background:
evidences have shown a strongly association between metabolic syndrome (MS), cardiovascular diseases and chronic low-grade inflammation, being this last, related with the occurrence of sarcopenia and atherosclerosis. Despite several benefits, the effects of resistance training (RT) on inflammatory profile are controversial. Thereby, this study aims to investigate the effects of a RT on the inflammatory profile of men with MS risk factors.
Methods:
fifteen sedentary men (57.53 ± 7.07 years old) with 2 or more MS components underwent a RT for 14 weeks (3 times per week), with intensity ranging between 40 and 70% of one repetition maximum. The dual-energy X-ray absorptiometry was used to body composition assessment and serum was collected to evaluate biochemical and inflammatory parameters before and after the RT.
Results:
despite the absence of changes in body weight, total muscular content and biochemical parameters, the individuals demonstrated a reduction on body fat content (p < 0.05). Furthermore, the RT resulted in lower circulating levels of tumor necrosis factor alpha and interleukin- 6 (p < 0.05), in higher levels of intelerukin-10 (p < 0.05) and in the stabilization of interleukin-1 beta and interferon-gamma concentrations. It was concluded that a moderate RT benefits inflammatory profile, contributing to a lower risk of cardiovascular diseases.
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