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Updated: Apr 5, 2026

A Customizable Approach for the Enzymatic Production and Purification of Diterpenoid Natural Products
Published on: October 4, 2019
Two new cassane-type diterpenes from the seeds of Caesalpinia crista
Qi-Bing Liu1, Ling Huang1, Li Zhang1
1a Department of Pharmacology , School of Pharmaceutical Science, Hainan Medical University , Haikou 571199 , China.
Abstract:
Two new cassane-type diterpenes, phangininoxys D and E (1 and 2), together with five known compounds were isolated from the seeds of Caesalpinia crista Linn. The structures of these compounds were elucidated by means of various spectroscopic analyses. All the isolated compounds were evaluated for cytotoxicity activities against HeLa, HT-29 and KB cell lines, and compound 7 showed moderate selective activities against KB cell line with an IC50 value of 17.1 μM.
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