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[Current aspects of therapy conversion for multiple sclerosis].

P Kolber1, F Luessi2, S G Meuth3

  • 1Klinik und Poliklinik für Neurologie, Forschungszentrum Translationale Neurowissenschaften (FTN), Forschungszentrum für Immuntherapie (FZI), Rhine Main Neuroscience Network (rmn2), Universitätsmedizin der Johannes Gutenberg-Universität Mainz, Langenbeckstr. 1, 55101, Mainz, Deutschland.

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|August 14, 2015
PubMed
Summary
This summary is machine-generated.

The increasing number of multiple sclerosis immunotherapies presents challenges for switching treatments. Expert consensus guides safe and effective therapy conversion strategies for managing this complex condition.

Keywords:
Clinical routineDisease-related competence network multiple sclerosisExpert consensusImmunotherapyWashout phase

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Area of Science:

  • Neurology
  • Immunology
  • Pharmacology

Context:

  • Growing availability of disease-modifying immunotherapies for multiple sclerosis (MS).
  • Therapy conversion is an emerging challenge due to complex adverse effect profiles and monitoring needs.
  • Need for evidence-based guidance on switching MS immunotherapies.

Purpose:

  • To provide an overview of current recommendations for immunotherapy conversion in multiple sclerosis.
  • To synthesize guidelines from key German neurological and multiple sclerosis societies.
  • To highlight the need for expert consensus in the absence of extensive clinical studies.

Summary:

  • Presents an overview of immunotherapy conversion strategies for multiple sclerosis.
  • Incorporates recommendations from the German Competence Network for MS, German MS Society, and German Society of Neurology.
  • Acknowledges that recommendations are based on expert consensus and theoretical considerations due to limited studies.

Impact:

  • Aids clinicians in managing complex therapy conversions for multiple sclerosis patients.
  • Provides a framework for safe and effective treatment switching in MS.
  • Highlights the importance of expert consensus in guiding clinical practice for evolving MS therapies.