Related Experiment Video
Updated: Jan 21, 2026

Isolation and Fluorescence Imaging for Single-particle Reconstruction of Chlamydomonas Centrioles
Published on: September 21, 2018
Building a ninefold symmetrical barrel: structural dissections of centriole assembly
1Max F. Perutz Laboratories, Medical University of Vienna, Vienna 1030, Austria gang.dong@meduniwien.ac.at.
Abstract:
Centrioles are short microtubule-based organelles with a conserved ninefold symmetry. They are essential for both centrosome formation and cilium biogenesis in most eukaryotes. A core set of five centriolar proteins has been identified and their sequential recruitment to procentrioles has been established. However, structures at atomic resolution for most of the centriolar components were scarce, and the underlying molecular mechanisms for centriole assembly had been a mystery--until recently. In this review, I briefly summarize recent advancements in high-resolution structural characterization of the core centriolar components and discuss perspectives in the field.
Related Concept Videos
Centrioles and Centrosomes
Near the end of the prophase, also called late prophase or...
Assembly of Complex Microtubule Structures
Symmetric Member in Bending
Deformations in a Symmetric Member in Bending
When the member is segmented into tiny cubic elements, it is observed that the primary stress...
Protein Complex Assembly
Many viruses self-assemble into a fully functional unit using the infected host cell to...
Beams with Symmetric Loadings
The M/EI...

