[Desquamation of the vascular endothelium after a normal birth and surgical delivery]

The desquamation of vascular endothelium was investigated in parturients after normal and operative delivery by cesarean section in dynamics up to the tenth day. There was increased endothelemia in both clinical groups up to the fifth postpartal day, after which the number of endothelial cells in plasma began to diminish lytically and it reached just the norm on the tenth day. Very high endothelemia up to 24th hour after cesarean section made impression. The increased desquamation of the vascular endothelium, as an objective manifestation for the presence of vascular lesions, in the clinical groups of women, examined by us, supported the concept for increased thrombotic risk during postpartal period. This risk is 6 times greater after operative deliveries by cesarean section according to literary data, which has been confirmed by our results for massive endothelial desquamation respectively for considerable vascular lesions within the first 24 hours after the operation and up to the fifth day inclusive. The possibility is discussed to add also vasoactive drugs with endothelium-stabilizing effect to the early antithrombotic prophylaxis with low doses of heparin in view of eventual reduction of vascular damages.