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Related Experiment Video

Updated: Apr 5, 2026

Author Spotlight: Overcoming Anti-VEGF Resistance Through Advanced Vascular Morphology Assessment in Choroidal Neovascularization
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[A man with vision problems after coronary angiography].

Mariet E Salomé1, Ben P W Jansen

  • 1Elisabeth-TweeSteden Ziekenhuis, afd. Neurologie, Tilburg.

Nederlands Tijdschrift Voor Geneeskunde
|August 15, 2015
PubMed
Summary

Transient cortical blindness, a rare complication of iodinated contrast agents, can occur after coronary angiography (CAG). This temporary vision loss resolved completely within two days in a 71-year-old male patient.

Area of Science:

  • Neurology
  • Radiology
  • Ophthalmology

Background:

  • Coronary angiography (CAG) is a common diagnostic procedure.
  • Iodinated contrast agents are frequently used in CAG.
  • Adverse reactions to contrast agents, though rare, can be serious.

Observation:

  • A 71-year-old male patient developed sudden bilateral cortical blindness immediately following CAG.
  • Neurologic assessment confirmed cortical blindness.
  • Cerebral CT-scan revealed occipital hyperdensity attributed to contrast agent accumulation and edema.

Findings:

  • The patient experienced a rare, transient neurological complication of iodinated contrast media.
  • The observed symptoms were consistent with contrast-induced encephalopathy.

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  • Complete visual recovery was noted within 48 hours.

    • Implications:

    • This case highlights the potential for rare visual complications following CAG.
    • Awareness of transient cortical blindness as a possible adverse effect of iodinated contrast agents is important for clinicians.
    • Further research may explore the mechanisms and risk factors for contrast-induced neurotoxicity.