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Identifying compound efficacy targets in phenotypic drug discovery

Markus Schirle1, Jeremy L Jenkins1

  • 1Developmental & Molecular Pathways, Novartis Institutes for BioMedical Research, Cambridge, MA 02139, USA.

Drug Discovery Today
|August 15, 2015
PubMed
Summary

Identifying drug targets and understanding compound mechanisms are crucial for drug development. This review covers key technologies for characterizing compound targets after phenotypic screening, aiding in assessing efficacy and potential liabilities.

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