Comparison of postoperative intraocular pressures after use of Miochol and Miostat

Over 100 cases of standard extracapsular cataract extraction with intraocular lens implantation were reviewed and the effects of two commercially available pharmacological agents were compared. The treatment groups received either acetylcholine chloride (Miochol) or carbachol (Miostat). Intraocular pressures were measured preoperatively and 20 to 24 hours postoperatively. The difference in mean pressures between the treatment groups was statistically significant. The results of the study showed Miostat to be the better pharmacological agent for controlling intraocular pressure 20 to 24 hours later. Since the majority of surgeons use Miochol rather than Miostat, the conclusions of this study appear to be significant.