Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Synaptic Signaling01:12

Synaptic Signaling

81.9K
Neurons communicate at synapses, or junctions, to excite or inhibit the activity of other neurons or target cells, such as muscles. Synapses may be chemical or electrical.
81.9K
Synaptic Signaling01:09

Synaptic Signaling

7.1K
Neurons communicate at synapses, or junctions, to excite or inhibit the activity of other neurons or target cells, such as muscles. Synapses may be chemical or electrical.
Most synapses are chemical, meaning an electrical impulse or action potential spurs the release of chemical messengers called neurotransmitters. The neuron sending the signal is called the presynaptic neuron, and the neuron receiving the signal is the postsynaptic neuron.
The presynaptic neuron fires an action potential that...
7.1K
Overview of Cell Signaling01:23

Overview of Cell Signaling

26.7K
Despite the protective membrane that separates a cell from the environment, cells need the ability to detect and respond to environmental changes. Additionally, cells often need to communicate with one another. Unicellular and multicellular organisms use a variety of cell signaling mechanisms to communicate with the environment.
Cells respond to many types of information, often through receptor proteins positioned on the membrane. For example, skin cells respond to and transmit touch...
26.7K
Overview of Cell Signaling01:23

Overview of Cell Signaling

5.1K
5.1K
Diversity in Cell Signaling Responses01:22

Diversity in Cell Signaling Responses

8.7K
The physiological function of a cell and cellular communication are outcomes of a range of extrinsic signals, intracellular signaling pathways, and cellular responses. No two cell types express the same repertoire of signaling components. Receptors are highly selective for their cognate ligands, but once activated, they can alter multiple cellular processes such as DNA transcription, protein synthesis, and metabolic activity. 
Graded and Abrupt Responses
Some signaling systems generate...
8.7K
Interactions Between Signaling Pathways01:19

Interactions Between Signaling Pathways

7.9K
Signaling cascades usually lack linearity. Multiple pathways interact and regulate one another, allowing cells to integrate and respond to diverse environmental stimuli.
Convergence and divergence, and cross-talk between signaling pathways
Two distinct signaling pathways can converge on a single functional unit, which may either be a single protein or a complex of proteins. The response is either functionally distinct or synergistic between the two pathways but different from the response...
7.9K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

The AMPA receptor life cycle: assembly, regulation and synaptic diversity.

Nature reviews. Neuroscience·2026
Same author

Control of microglial dynamics by the Arp2/3 complex and the autism- and schizophrenia-associated protein CYFIP1.

Proceedings of the National Academy of Sciences of the United States of America·2026
Same author

Splicing, RNA editing, and auxiliary subunits shaped AMPA receptor function through coordinated evolution.

Trends in neurosciences·2026
Same author

GLP-1 activates K<sub>ATP</sub> channels in coronary pericytes as the effector of brain-gut-heart signalling mediating cardioprotection.

Nature communications·2026
Same author

The vascular contribution to cognitive decline in ageing and dementia.

Nature reviews. Neuroscience·2025
Same author

Evolution of iGluR ligand specificity, polyamine regulation, and ion selectivity inferred from a placozoan epsilon receptor.

Communications biology·2025

Related Experiment Video

Updated: Apr 5, 2026

Analyzing the Size, Shape, and Directionality of Networks of Coupled Astrocytes
10:10

Analyzing the Size, Shape, and Directionality of Networks of Coupled Astrocytes

Published on: October 4, 2018

9.4K

Coupling cellular metabolism to neuronal signalling

Derek Bowie1, David Attwell2

  • 1Department of Pharmacology and Therapeutics, McGill University, Montréal, Québec, Canada, H3G 1Y6.

The Journal of Physiology
|August 15, 2015
PubMed
Summary

No abstract available in PubMed .

More Related Videos

Author Spotlight: Advances in Brain Energy Metabolism Research Using the Drosophila Model
07:18

Author Spotlight: Advances in Brain Energy Metabolism Research Using the Drosophila Model

Published on: October 27, 2023

1.3K
Microfluidic Chip for Axonal Injury Models Construction and Enabling Multi-Omics Analysis
11:00

Microfluidic Chip for Axonal Injury Models Construction and Enabling Multi-Omics Analysis

Published on: October 14, 2025

1.5K

Related Experiment Videos

Last Updated: Apr 5, 2026

Analyzing the Size, Shape, and Directionality of Networks of Coupled Astrocytes
10:10

Analyzing the Size, Shape, and Directionality of Networks of Coupled Astrocytes

Published on: October 4, 2018

9.4K
Author Spotlight: Advances in Brain Energy Metabolism Research Using the Drosophila Model
07:18

Author Spotlight: Advances in Brain Energy Metabolism Research Using the Drosophila Model

Published on: October 27, 2023

1.3K
Microfluidic Chip for Axonal Injury Models Construction and Enabling Multi-Omics Analysis
11:00

Microfluidic Chip for Axonal Injury Models Construction and Enabling Multi-Omics Analysis

Published on: October 14, 2025

1.5K