Multiple Segmental Eccrine Spiradenoma with a Zosteriform Pattern: A Case Report and Literature Review
Fang Ren1, Zhili Hu2, Qingtao Kong2
1Southern Medical University, Nanjing, China. ; Department of Dermatology, Jinling Hospital, Nanjing University of Medicine, Nanjing, China.
Annals of Dermatology
|August 15, 2015
Summary
This case study details an unusual presentation of eccrine spiradenoma, a rare skin tumor, with a zosteriform distribution and unique triggers like perspiration. The findings contribute to understanding this rare dermatological condition.
Area of Science:
- Dermatology
- Oncology
- Pathology
Background:
- Eccrine spiradenoma typically presents as solitary, tender nodules.
- Multifocal or zosteriform presentations are exceptionally rare, posing diagnostic challenges.
Observation:
- A 32-year-old woman presented with a 20-year history of itchy, zosteriform lesions on her back and forearm.
- Lesions worsened with perspiration or spicy food, an unprecedented observation.
- A preceding injection was noted, though its role remains undetermined.
Findings:
- This case represents a rare instance of multiple segmental eccrine spiradenoma.
- The patient's unique symptom exacerbation provides novel clinical insights.
- A review of 22 similar cases was conducted to identify clinical characteristics.
Implications:
- Enhanced understanding of rare eccrine spiradenoma variants.
- Improved diagnostic criteria for multifocal and zosteriform eccrine spiradenoma.
- Potential for new treatment strategies based on identified clinical patterns.
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