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Updated: Apr 5, 2026

CT-guided Preoperative Localization of Pulmonary Nodules Using a Glucose Test and Tissue Adhesive
Published on: January 30, 2026
Preoperative computed tomography-guided percutaneous localization of ground glass pulmonary opacity with polylactic
Mu Hu1, Xiuyi Zhi1, Jian Zhang1
1Thoracic Surgery Department, Xuanwu Hospital Capital Medical University Beijing, China.
Abstract:
Localization of a ground glass nodule is a difficult challenge for thoracic surgeons, especially for ground glass opacities (GGOs) less than 10 mm in diameter. In this study we implement a new method for preoperative localization of pulmonary (GGOs). From October 2013 to December 2014, computed tomography-guided percutaneous polylactic acid injection localizations were performed for five pulmonary nodules in five patients (2 men and 3 women; mean age, 59.8 years; range, 54-65 years). The injection was feasible in all patients and the localization effect was excellent. The total procedure duration was 12.6 minutes (range; 10-15) and the volume of polylactic acid injected was 0.38 mL. The wedge resections were easily and successfully performed in all five cases. The cutting margin was no less than 2 cm from the lesion. This technique is promising for the determination of GGO location in thoracoscopic surgery for wedge resection.

