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Immunogenicity of pneumococcal vaccination in a patient with sickle hemoglobinopathy: a case report
E Leila Jerome Clay1, Tierra Burrell2, Thomas Belhorn3
1Division of Hematology and Oncology, Departments of Pediatrics and Internal Medicine, Georgia Regents University Augusta, Georgia, USA.
Clinical Case Reports
|August 15, 2015
Abstract:
Despite decrease in morbidity and mortality from invasive pneumococcal disease (IPD), individuals with asplenia remain at risk for IPD compared to the general population. This report describes a young adult with hemoglobin SD and documented splenic autoinfarction with pneumococcal sepsis, meningitis, and pneumonia within seven months of immunization with PPSV-23.
