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Feedback Inhibition00:46

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Biochemical reactions are occurring constantly in cells, converting starting substances to different products, usually with the help of enzymes that speed the reactions. Without enzymes, it would take far too long for most reactions to occur to be useful to the cell!
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In most cases, excessive hormone production is prevented by negative feedback—a loop that starts with a stimulus inducing the release of a particular substance, like a hormone, to maintain a certain level before triggering a signal that results in a decrease in further release of the hormone.
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Synthesis of new DNA molecules is carried out by the enzyme DNA polymerase, which adds nucleotides on the daughter strand complementary to the template DNA strand. DNA polymerase has a higher affinity to add the correct base and ensures fidelity during DNA replication. Furthermore,  it exhibits proofreading activity during replication, using an exonuclease domain that cuts off incorrect nucleotides from the nascent DNA strand.
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Updated: Apr 5, 2026

Scanning Skeletal Remains for Bone Mineral Density in Forensic Contexts
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The authors reply

David R McIlroy1, David Farkas, Matthew Matto

  • 1Anaesthesia & Perioperative Medicine, Alfred Hospital & Monash University, Melbourne, VIC, Australia Department of Anesthesiology, New York Presbyterian Hospital, New York, NY.

Critical Care Medicine
|August 15, 2015
PubMed
Summary

No abstract available in PubMed .

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