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Updated: Aug 1, 2026

Non-Invasive Model of Neuropathogenic Escherichia coli Infection in the Neonatal Rat
Published on: October 29, 2014
[Infectious meningitis in the adult: 3-year clinical experience]
Abstract:
In order to establish the epidemiologic features of infectious meningitis in the adult population in our environment, the experience of the Department of Neurology of the Hospital del Rey during the 3-year period, from 1984 to 1986, has been analyzed. Three-hundred-ninety episodes were handled, of which, 51% were acute bacterial meningitis, 45% were acute lymphocytic meningitis, 26% were tuberculous meningitis, 1% were brucellar meningitis and 0.5% were due to Candida albicans. Acute bacterial meningitis predominated in winter, whereas acute lymphocytic meningitis predominated in summer (p less than 0.001). Forty-seven percent of acute bacterial meningitis were due to Neisseria meningitidis and 14.5% of acute lymphocytic meningitis with virologic study, were due to Herpesviridae. The mortality rate of acute bacterial meningitis was 8.5% and that of tuberculous meningitis was 10%. In order to emphasize the importance of these processes, the main epidemiologic data are compared with that of other studies.
Insights
This study analyzed 390 infectious meningitis cases from 1984-1986, finding acute bacterial meningitis and acute lymphocytic meningitis were most common. Seasonal patterns and specific pathogens like Neisseria meningitidis were identified.
Area of Science:
- Neurology
- Infectious Diseases
- Epidemiology
Context:
- Analysis of infectious meningitis cases in an adult population.
- Data collected from the Department of Neurology, Hospital del Rey, between 1984 and 1986.
- Review of 390 meningitis episodes.
Purpose:
- To establish the epidemiologic features of infectious meningitis in the local adult population.
- To identify the incidence and characteristics of different meningitis types.
- To compare findings with existing studies.
Summary:
- Acute bacterial meningitis accounted for 51% of cases, acute lymphocytic meningitis for 45%, and tuberculous meningitis for 26%.
- Bacterial meningitis peaked in winter, while lymphocytic meningitis peaked in summer (p < 0.001).
- Neisseria meningitidis was a primary cause of bacterial meningitis (47%), and Herpesviridae of lymphocytic meningitis (14.5%).
- Mortality rates were 8.5% for acute bacterial meningitis and 10% for tuberculous meningitis.
Impact:
- Highlights the significant burden of infectious meningitis in the studied adult population.
- Provides crucial data for understanding seasonal variations and causative agents.
- Informs public health strategies and clinical management of meningitis.
Related Concept Videos
Bacterial Meningitis
Viral Meningitis
Cryptococcal Meningitis
Bacterial Meningitis I: Introduction
Bacterial Meningitis II: Pathophysiology
Encephalitis l: Introduction

