Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Operant Conditioning Intervention01:24

Operant Conditioning Intervention

657
Operant conditioning serves as a foundational principle in therapeutic interventions aimed at modifying maladaptive behaviors. Central to this approach is the notion that behaviors, both adaptive and maladaptive, are learned through reinforcement. By analyzing the environmental factors that reinforce problematic behaviors, clinicians can design interventions to weaken these reinforcements and replace maladaptive behaviors with healthier alternatives.
In operant conditioning, behaviors that are...
657
Obsessive-Compulsive Disorder01:28

Obsessive-Compulsive Disorder

896
Obsessive-compulsive disorder (OCD) is a mental health condition characterized by recurrent obsessions, compulsions, or both, which consume significant time and interfere with daily functioning. Obsessions involve persistent, intrusive, and unwanted thoughts, images, or urges that evoke anxiety. Common examples include irrational fears of contamination or harm. Compulsions are repetitive behaviors or mental acts performed to reduce the anxiety caused by obsessions. For instance, individuals...
896
Rational Emotive Behavior Therapy01:24

Rational Emotive Behavior Therapy

667
Cognitive-behavioral therapies (CBTs) are grounded in the belief that our thoughts profoundly influence our emotions and actions. Advocates of CBT emphasize three core assumptions: first, that cognitions are identifiable and measurable; second, that they are central to psychological functioning; and third, that irrational or maladaptive beliefs can be replaced with rational and adaptive ones. This transformative approach to therapy has paved the way for specific models such as Albert...
667
Cognitive Therapy01:25

Cognitive Therapy

1.4K
Cognitive therapy, pioneered by Aaron T. Beck in the 1960s, is a structured approach to addressing psychological distress by focusing on the influence of thoughts on emotions and behaviors. All cognitive therapies involve the basic assumption that human beings have control over their feelings, and that how individuals feel about something depends on how they think about it. Unlike psychoanalytic methods that delve into unconscious processes or humanistic approaches emphasizing...
1.4K
Behavior Therapy01:22

Behavior Therapy

957
Behavior therapy incorporates diverse techniques rooted in classical conditioning principles to address maladaptive behaviors and anxiety disorders. These methods aim to reduce avoidance behaviors, foster adaptive coping mechanisms, and alter associations between stimuli and responses, making them effective in a wide range of therapeutic contexts.
Exposure therapy is a cornerstone of behavioral treatment for anxiety disorders. It involves systematic exposure to feared stimuli, either in real...
957
Anxiety: Overview01:18

Anxiety: Overview

1.3K
Anxiety is a common mental disorder featuring excessive worry, fear, and apprehension, significantly affecting daily life. People with anxiety disorders experience persistent and intense anxiety, interrupting their everyday functioning.
Individuals with anxiety often experience a range of physical and emotional symptoms, including sweating, trembling, tachycardia, and disturbances in sleep patterns. These symptoms vary in intensity and frequency but are generally disruptive and distressing.
1.3K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Beneficial Herb-Drug Interaction of Shenqi Oral Liquid on Atorvastatin: A Pharmacokinetic and Pharmacodynamic Investigation in Rats with Hyperlipidemia.

Chinese journal of integrative medicine·2026
Same author

Neutropenia Associated With Trazodone: A Rare Case.

Journal of clinical psychopharmacology·2026
Same author

Predicting the rapid progression of coronary artery lesions in patients with acute coronary syndrome based on machine learning.

Frontiers in cardiovascular medicine·2025
Same author

[Exploration of pharmacodynamic material basis and mechanism of Jinbei Oral Liquid against idiopathic pulmonary fibrosis based on UHPLC-Q-TOF-MS/MS and network pharmacology].

Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica·2025
Same author

Combined enriched environment and fluoxetine enhance myelin protein expression in the prefrontal cortex of a chronic unpredictable stress depression model.

Behavioral and brain functions : BBF·2025
Same author

Intestinal Absorption Characteristics and Reciprocal Interactions of <i>Forsythiae Fructus</i> and <i>Lonicerae Japonicae Flos</i>-Containing Chinese Herbal Formulation with Human Gut Microbiome.

The American journal of Chinese medicine·2025

Related Experiment Video

Updated: Apr 5, 2026

Protocol for Repetitive Transcranial Magnetic Stimulation with Symptom Provocation to Treat Obsessive-compulsive Disorder
11:17

Protocol for Repetitive Transcranial Magnetic Stimulation with Symptom Provocation to Treat Obsessive-compulsive Disorder

Published on: November 25, 2025

811

Highly efficacious cognitive-coping therapy for overt or covert compulsions.

Xian-Zhang Hu1, Jian-Dong Ma2, Ping Huang3

  • 1The Second Hospital of Xinxiang Medical University, Xinxiang City 453002, Henan Province, PR China; Workstation of Henan Province for Psychiatry experts, Kaifeng City 475003, Henan Province, PR China.

Psychiatry Research
|August 16, 2015
PubMed
Summary

Pharmacotherapy plus cognitive-coping therapy (pCCT) offers a more effective treatment for obsessive-compulsive disorder (OCD) than standard pharmacotherapy plus psychological support. This approach significantly reduces symptom severity in adult OCD patients with overt or covert compulsions.

Keywords:
Cognitive-coping therapyOCDOCD with covert compulsionsOCD with overt compulsionsTreatment

More Related Videos

Signal Attenuation as a Rat Model of Obsessive Compulsive Disorder
09:29

Signal Attenuation as a Rat Model of Obsessive Compulsive Disorder

Published on: January 9, 2015

16.0K
Exploring the Neural Correlates of Cognitive Reappraisal in Obsessive-Compulsive Disorder Using Task-based Functional Magnetic Resonance Imaging
09:14

Exploring the Neural Correlates of Cognitive Reappraisal in Obsessive-Compulsive Disorder Using Task-based Functional Magnetic Resonance Imaging

Published on: March 14, 2025

1.3K

Related Experiment Videos

Last Updated: Apr 5, 2026

Protocol for Repetitive Transcranial Magnetic Stimulation with Symptom Provocation to Treat Obsessive-compulsive Disorder
11:17

Protocol for Repetitive Transcranial Magnetic Stimulation with Symptom Provocation to Treat Obsessive-compulsive Disorder

Published on: November 25, 2025

811
Signal Attenuation as a Rat Model of Obsessive Compulsive Disorder
09:29

Signal Attenuation as a Rat Model of Obsessive Compulsive Disorder

Published on: January 9, 2015

16.0K
Exploring the Neural Correlates of Cognitive Reappraisal in Obsessive-Compulsive Disorder Using Task-based Functional Magnetic Resonance Imaging
09:14

Exploring the Neural Correlates of Cognitive Reappraisal in Obsessive-Compulsive Disorder Using Task-based Functional Magnetic Resonance Imaging

Published on: March 14, 2025

1.3K

Area of Science:

  • Psychiatry
  • Clinical Psychology

Background:

  • Obsessive-compulsive disorder (OCD) is a severe psychiatric disorder with limitations in current pharmacotherapy and cognitive-behavioral therapy (CBT).
  • There is a need for more efficacious treatments for adult OCD patients, including those with overt or covert compulsions.

Purpose of the Study:

  • To investigate the efficacy of pharmacotherapy plus cognitive-coping therapy (pCCT) compared to pharmacotherapy plus psychological support (PPS) in treating adult OCD patients.
  • To assess the effectiveness of pCCT for both overt and covert compulsions in OCD.

Main Methods:

  • A randomized controlled trial involving 215 adult OCD patients.
  • Patients were allocated to either pCCT (n=108) or PPS (n=107).
  • Symptom severity was measured using the Yale-Brown Obsessive Compulsive Scale (Y-BOCS) at acute and long-term follow-up.

Main Results:

  • pCCT group showed significantly lower Y-BOCS scores than the PPS group in both acute (<3 months) and long-term follow-up.
  • Symptom severity was significantly reduced in pCCT for both overt and covert compulsions.
  • Effect size, response rate, and remission rate were significantly higher in the pCCT group compared to the PPS group.

Conclusions:

  • Pharmacotherapy plus cognitive-coping therapy (pCCT) is an efficacious treatment for adult OCD patients with overt or covert compulsions.
  • pCCT demonstrates superior outcomes in symptom reduction, response, and remission rates compared to pharmacotherapy plus psychological support.
  • pCCT represents a potential therapeutic option for managing obsessive-compulsive disorder.