Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Raman Spectroscopy: Overview01:20

Raman Spectroscopy: Overview

2.6K
The underlying principle of Raman spectroscopy is based on the interaction between light and matter, specifically molecules' inelastic scattering of photons. When a monochromatic beam of light, typically from a laser source, interacts with a sample, most scattered light has the same frequency as the incident light. This is known as Rayleigh scattering.
However, a small fraction of the scattered light exhibits a frequency shift due to the exchange of energy between the incident photons and...
2.6K
Raman Spectroscopy Instrumentation: Overview01:26

Raman Spectroscopy Instrumentation: Overview

1.8K
A conventional Raman spectrophotometer includes a laser source, a sample holding system, a wavelength selector, and a detector.
The monochromatic laser source, typically using visible or near-infrared radiation, generates a highly focused beam of light. This light interacts with the molecules of the sample, scattering some of the light. Liquid and gaseous samples are usually tested in ordinary glass capillaries, while solids can be analyzed as powders packed in capillaries or as potassium...
1.8K
Double Resonance Techniques: Overview01:12

Double Resonance Techniques: Overview

853
Double resonance techniques in Nuclear Magnetic Resonance (NMR) spectroscopy involve the simultaneous application of two different frequencies or radiofrequency pulses to manipulate and observe two distinct nuclear spins. One important application of double resonance is spin decoupling, which selectively suppresses coupling with one type of nucleus while observing the NMR signal from another nucleus, simplifying the spectrum and enhancing resolution.
Spin decoupling is usually achieved by...
853
¹³C NMR: Distortionless Enhancement by Polarization Transfer (DEPT)01:20

¹³C NMR: Distortionless Enhancement by Polarization Transfer (DEPT)

1.9K
When proton-coupled carbon-13 spectra are simplified by a broadband proton decoupling technique, structural information about the coupled protons is lost. Distortionless enhancement by polarization transfer (DEPT) is a technique that provides information on the number of hydrogens attached to each carbon in a molecule. While the DEPT experiment utilizes complex pulse sequences, the pulse delay and flip angle are specifically manipulated. The resulting signals have different phases depending on...
1.9K
Insensitive Nuclei Enhanced by Polarization Transfer (INEPT)01:15

Insensitive Nuclei Enhanced by Polarization Transfer (INEPT)

1.2K
Insensitive Nuclei Enhanced by Polarization Transfer (INEPT) is an advanced Nuclear Magnetic Resonance (NMR) technique specifically designed to detect and enhance the signals of low-abundance nuclei, such as carbon-13 and nitrogen-15, in small molecules. The fundamental principle behind INEPT is the transfer of polarization from a more abundant and highly polarizable nucleus, typically hydrogen-1, to the low-abundance nucleus of interest. This process effectively boosts the NMR signal of the...
1.2K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Engineering low-symmetry colloidal crystals with optical anisotropies.

Science advances·2026
Same author

Strong field quantum control of bimolecular reactions.

The Journal of chemical physics·2025
Same author

33 Unresolved Questions in Nanoscience and Nanotechnology.

ACS nano·2025
Same author

Retraction of "Bisboronic Acids for Selective, Physiologically Relevant Direct Glucose Sensing with Surface-Enhanced Raman Spectroscopy".

Journal of the American Chemical Society·2024
Same author

Discovering polyelemental nanostructures with redistributed plasmonic modes through combinatorial synthesis.

Science advances·2023
Same author

The Primarily Undergraduate Nanomaterials Cooperative: A New Model for Supporting Collaborative Research at Small Institutions on a National Scale.

ACS nanoscience Au·2023

Related Experiment Video

Updated: Apr 5, 2026

Ultrafast Time-resolved Near-IR Stimulated Raman Measurements of Functional π-conjugate Systems
09:57

Ultrafast Time-resolved Near-IR Stimulated Raman Measurements of Functional π-conjugate Systems

Published on: February 10, 2020

7.7K

Tip-Enhanced Raman Spectroscopy with Picosecond Pulses.

Jordan M Klingsporn1, Matthew D Sonntag1, Tamar Seideman1

  • 1Northwestern University, Department of Chemistry, 2145 Sheridan Road, Evanston, Illinois 60208, United States.

The Journal of Physical Chemistry Letters
|August 16, 2015
PubMed
Summary

Tip-enhanced Raman spectroscopy (TERS) achieves high-resolution surface chemistry analysis. Combining ultrafast lasers with TERS reveals transient molecular dynamics, showing signal decay under pulsed excitation.

Keywords:
kineticspicosecond excitationplasmonicstip-enhanced raman spectroscopyultrafast raman spectroscopy

More Related Videos

Biomolecular Imaging of Cellular Uptake of Nanoparticles using Multimodal Nonlinear Optical Microscopy
07:13

Biomolecular Imaging of Cellular Uptake of Nanoparticles using Multimodal Nonlinear Optical Microscopy

Published on: May 16, 2022

2.4K
Multiplex Chemical Imaging Based on Broadband Stimulated Raman Scattering Microscopy
09:57

Multiplex Chemical Imaging Based on Broadband Stimulated Raman Scattering Microscopy

Published on: July 25, 2022

4.7K

Related Experiment Videos

Last Updated: Apr 5, 2026

Ultrafast Time-resolved Near-IR Stimulated Raman Measurements of Functional π-conjugate Systems
09:57

Ultrafast Time-resolved Near-IR Stimulated Raman Measurements of Functional π-conjugate Systems

Published on: February 10, 2020

7.7K
Biomolecular Imaging of Cellular Uptake of Nanoparticles using Multimodal Nonlinear Optical Microscopy
07:13

Biomolecular Imaging of Cellular Uptake of Nanoparticles using Multimodal Nonlinear Optical Microscopy

Published on: May 16, 2022

2.4K
Multiplex Chemical Imaging Based on Broadband Stimulated Raman Scattering Microscopy
09:57

Multiplex Chemical Imaging Based on Broadband Stimulated Raman Scattering Microscopy

Published on: July 25, 2022

4.7K

Area of Science:

  • Surface science
  • Spectroscopy
  • Nanotechnology

Background:

  • Tip-enhanced Raman spectroscopy (TERS) offers nanometer spectroscopic and submolecular spatial resolution for surface chemistry.
  • Integrating ultrafast spectroscopy with TERS enables picosecond and potentially femtosecond temporal resolution.

Purpose of the Study:

  • To couple an optical parametric oscillator (OPO) with a scanning tunneling microscopy (STM)-TERS system.
  • To excite the plasmonic tip using picosecond pulsed laser excitation.
  • To investigate the temporal dynamics of TERS signals under ultrafast excitation.

Main Methods:

  • Utilized an optical parametric oscillator (OPO) for picosecond pulsed excitation.
  • Employed a scanning tunneling microscopy (STM)-TERS setup.
  • Observed tip-enhanced Raman (TER) spectra for resonant adsorbates.

Main Results:

  • The plasmonic tip remained undamaged during OPO excitation.
  • TER spectra were successfully obtained for two resonant adsorbates.
  • A decay of the TERS signal was observed on the timescale of 10s of seconds under ultrafast pulsed excitation, unlike continuous-wave excitation.

Conclusions:

  • Picosecond pulsed excitation can be effectively used with STM-TERS without damaging the tip.
  • The study demonstrates the capability of TERS to probe time-resolved surface dynamics.
  • Analysis of decay mechanisms provides insights into ultrafast processes at the nanoscale.