Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

The Monomeric Conformational Ensembles of Aβ40 and Aβ42 Encode Their Differential Amyloid Aggregation Propensity.

The journal of physical chemistry. B·2026
Same author

Tumor DNA methylation subtypes predict immunotherapy outcomes in pleural mesothelioma patients in the NIBIT-EPI-MESO study.

Nature genetics·2026
Same author

Endovascular Treatment for Symptomatic Hypogastric Artery Stenosis or Occlusion: A Systematic Review and Meta-Analysis.

Annals of vascular surgery·2026
Same author

Physiologically controlled release from an in situ forming liposomal depot.

Journal of controlled release : official journal of the Controlled Release Society·2026
Same author

Risk Factors for Neuropathic Pain in Digital Amputations.

Journal of clinical medicine·2026
Same author

Ist2 is a phospholipid scramblase that links lipid transport at the ER to organelle homeostasis.

The Journal of cell biology·2025

Related Experiment Video

Updated: Apr 5, 2026

Preparation of Hollow Polystyrene Particles and Microcapsules by Radical Polymerization of Janus Droplets Consisting of Hydrocarbon and Fluorocarbon Oils
07:01

Preparation of Hollow Polystyrene Particles and Microcapsules by Radical Polymerization of Janus Droplets Consisting of Hydrocarbon and Fluorocarbon Oils

Published on: January 25, 2018

10.6K

Polystyrene Nanoparticles Perturb Lipid Membranes.

Giulia Rossi1,2,3, Jonathan Barnoud1,2,3, Luca Monticelli1,2,3

  • 1INSERM, UMR-S665, Paris, F-75015, France.

The Journal of Physical Chemistry Letters
|August 16, 2015
PubMed
Summary

Nanosized polystyrene particles easily enter marine wildlife cell membranes, disrupting their structure and function. This molecular-level damage to membranes can negatively impact cellular activities and protein function.

Keywords:
coarse-grained modelslipid membranesmolecular dynamicsnanoparticlepolymersrafts

More Related Videos

Using Polystyrene-block-polyacrylic acid-coated Metal Nanoparticles as Monomers for Their Homo- and Co-polymerization
09:02

Using Polystyrene-block-polyacrylic acid-coated Metal Nanoparticles as Monomers for Their Homo- and Co-polymerization

Published on: July 9, 2015

13.0K
Electroactive Polymer Nanoparticles Exhibiting Photothermal Properties
10:16

Electroactive Polymer Nanoparticles Exhibiting Photothermal Properties

Published on: January 8, 2016

14.4K

Related Experiment Videos

Last Updated: Apr 5, 2026

Preparation of Hollow Polystyrene Particles and Microcapsules by Radical Polymerization of Janus Droplets Consisting of Hydrocarbon and Fluorocarbon Oils
07:01

Preparation of Hollow Polystyrene Particles and Microcapsules by Radical Polymerization of Janus Droplets Consisting of Hydrocarbon and Fluorocarbon Oils

Published on: January 25, 2018

10.6K
Using Polystyrene-block-polyacrylic acid-coated Metal Nanoparticles as Monomers for Their Homo- and Co-polymerization
09:02

Using Polystyrene-block-polyacrylic acid-coated Metal Nanoparticles as Monomers for Their Homo- and Co-polymerization

Published on: July 9, 2015

13.0K
Electroactive Polymer Nanoparticles Exhibiting Photothermal Properties
10:16

Electroactive Polymer Nanoparticles Exhibiting Photothermal Properties

Published on: January 8, 2016

14.4K

Area of Science:

  • Environmental Science
  • Molecular Biology
  • Biophysics

Background:

  • Polystyrene is a common marine pollutant that degrades into microplastics.
  • Microplastic ingestion by marine wildlife is widespread, but cellular impacts are unknown.
  • Studying molecular-level membrane interactions in vivo is challenging.

Purpose of the Study:

  • To investigate the effects of nanosized polystyrene particles on model biological membranes.
  • To understand the molecular mechanisms of polystyrene interaction with cell membranes.

Main Methods:

  • Coarse-grained molecular dynamics simulations were employed.
  • Model lipid membranes were simulated in the presence of polystyrene nanoparticles.

Main Results:

  • Polystyrene nanoparticles readily permeated into lipid membranes.
  • Polystyrene altered membrane structure, reduced molecular diffusion, and softened the membrane.
  • Polystyrene stabilized raft-like domains, affecting membrane lateral organization.

Conclusions:

  • Polystyrene nanoparticles disrupt biological membrane structure and dynamics at the molecular level.
  • These changes can impair membrane protein activity and cellular function.
  • Findings highlight potential cellular-level risks of microplastic pollution in marine ecosystems.