Related Experiment Video
Updated: Apr 5, 2026

Closure of a Patent Foramen Ovale PFO: An Intervention Sequence
Published on: December 23, 2022
Predisposing Factors for Spontaneous Closure of Congenital Portosystemic Shunts
Massimiliano Paganelli1, José E Lipsich2, Marco Sciveres3
1Pediatric Gastroenterology, Hepatology, and Nutrition, CHU Sainte-Justine, Université de Montréal, Montreal, Québec, Canada.
Abstract:
In a review of 382 cases of congenital portosystemic shunt, we found that presentation with neonatal cholestasis strongly predicts spontaneous closure of intrahepatic shunts (OR 8.3, 95% CI 3.4-20.2). Spontaneous closure before the 24th month of age is more likely for distal or multiple shunts, but rare for patent ductus venosus.
Related Concept Videos
Esophageal Varices-I: Introduction
Mitral Stenosis I: Introduction
Fetal Circulation
Two umbilical arteries transport blood from the fetus to the placenta. At the placenta, the blood absorbs oxygen and nutrients while simultaneously eliminating waste products. This oxygen-enriched and nutrient-rich blood then returns to the fetus through one...
Mitral Valve Prolapse I: Introduction

