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SnapShot: Interactions between B Cells and T Cells

Stuart G Tangye1, Robert Brink1, Christopher C Goodnow1

  • 1Immunology Division, Garvan Institute of Medical Research, Darlinghurst NSW 2010, Australia; St Vincent's Clinical School, 2010 UNSW, Australia.

Cell
|August 16, 2015
PubMed

Dynamic interactions between B and T cells underpin the development of adaptive humoral immune responses to infections and vaccines. Recent advances in the molecular and spatiotemporal control of these interactions during primary responses have contributed greatly to elucidating the molecular pathogenesis of numerous immunodeficiency and autoimmune diseases. The next challenge is to determine how and where memory B and T cells interact during secondary responses to facilitate the rapid and robust response that characterizes anamnestic immunity.

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