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Acne Infection01:27

Acne Infection

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Acne is a multifactorial skin condition primarily affecting adolescents and young adults, with a global prevalence estimated to exceed 75% in this demographic. The condition is characterized by the formation of comedones (blackheads and whiteheads), papules, pustules, nodules, and, in severe cases, cysts, particularly in areas rich in sebaceous glands such as the face, neck, chest, and back. The pathogenesis involves increased sebum production, follicular hyperkeratinization, colonization by...
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Peptic Ulcer Disease IV: Management01:26

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Medical treatment strategies for peptic ulcers encompass various methods. The primary goal of treatment is to diminish gastric acidity and strengthen mucosal defense mechanisms.
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Urinary Tract Infection III: Diagnostic Studies and Interprofessional Care01:30

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A healthcare provider can diagnose a urinary tract infection (UTI) through several methods:Medical History and Symptoms: The provider will take a detailed medical history and ask about symptoms such as frequent urination, burning sensation during urination, and lower abdominal pain.Urinalysis: A clean-catch urine sample is collected in a sterile container and tested for the presence of bacteria, white blood cells (leukocytes), nitrites, blood, and protein. The presence of leukocytes and...
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Acute Pyelonephritis II: Diagnostic Studies and Management01:28

Acute Pyelonephritis II: Diagnostic Studies and Management

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Introduction:For diagnosing acute pyelonephritis, a comprehensive patient history is collected to identify symptoms such as dysuria, frequent or urgent urination, flank pain, or costovertebral angle (CVA) tenderness that may suggest a kidney infection.Physical ExaminationDuring the physical examination, CVA tenderness is assessed. This involves gentle percussion over the costovertebral angle, where tenderness often indicates a kidney infection.Diagnostic TestsUrinalysis: Used to identify white...
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Urinary Tract Infection IV: Nursing Management01:17

Urinary Tract Infection IV: Nursing Management

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In managing urinary tract infections (UTIs) in nursing, a comprehensive assessment is essential. Begin by gathering subjective data, such as the patient’s complaints of dysuria (painful urination), urinary frequency, urgency, suprapubic pain, and any lower abdominal discomfort. This information can be complemented by questions regarding previous UTIs, sexual activity, and personal hygiene practices, which can provide insight into risk factors. Objective assessment should focus on signs...
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Updated: Apr 5, 2026

Author Spotlight: Ultrasound-Guided Needle Release Combined with Corticosteroid Injection for the Treatment of Supinator Syndrome
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Update on Hidradenitis Suppurative (Part II): Treatment.

A Martorell1, F J García2, D Jiménez-Gallo3

  • 1Servicio de Dermatología, Hospital de Manises, Valencia, España.

Actas Dermo-Sifiliograficas
|August 17, 2015
PubMed
Summary
This summary is machine-generated.

Hidradenitis suppurativa treatment is evolving, focusing on systemic inflammation control. Novel therapies, including biologic drugs like adalimumab, are being investigated for moderate to severe cases.

Keywords:
Acne inversaAcné inversaAdalimumabBiologic therapyCirugíaHidradenitis suppurativaHidradenitis supurativaSurgerySystemic treatmentTerapia biológicaTerapia sistémica

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Area of Science:

  • Dermatology
  • Immunology
  • Pharmacology

Background:

  • Hidradenitis suppurativa (HS) is a prevalent, serious skin condition with poorly established treatments.
  • Moderate to severe HS involves significant systemic inflammation.
  • Current treatment goals include controlling systemic inflammation and reducing cutaneous manifestations, sometimes requiring surgery.

Purpose of the Study:

  • To review and analyze the various treatment modalities available for hidradenitis suppurativa.
  • To discuss recent advancements in understanding HS and emerging therapeutic strategies.

Main Methods:

  • Literature review of current and emerging treatments for hidradenitis suppurativa.
  • Analysis of clinical trial data, particularly for biologic agents like adalimumab.

Main Results:

  • Treatment for HS remains challenging, with a focus on managing systemic inflammation.
  • Biologic drugs, notably adalimumab, show promise and are under investigation in clinical trials.
  • Surgery may be necessary for severe cutaneous inflammation.

Conclusions:

  • Effective treatment strategies for hidradenitis suppurativa are still developing.
  • Biologics represent a significant advancement in managing HS, targeting underlying inflammation.
  • A comprehensive approach combining medical and potentially surgical interventions is crucial.