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Updated: Apr 5, 2026

Isolation of CD133+ Liver Stem Cells for Clonal Expansion
Published on: October 10, 2011
Liver Stem Cells: Experimental Findings and Implications for Human Liver Disease
George K Michalopoulos1, Zahida Khan2
1Department of Pathology University of Pittsburgh School of Medicine.
Abstract:
Evidence from human histopathology and experimental studies with rodents and zebrafish has shown that hepatocytes and cholangiocytes may function as facultative stem cells for each other in conditions of impaired regeneration. The interpretation of the findings derived from these studies has generated considerable discussion and some controversies. This review examines the evidence obtained from the different experimental models and considers implications that these studies may have for human liver disease.
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