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Related Experiment Videos

Energy expenditure economy induced by decrease in lean body mass in anorexia nervosa.

J C Melchior1, D Rigaud, R Rozen

  • 1Unité INSERM U. 286, CHU Bichat, Paris, France.

European Journal of Clinical Nutrition
|November 1, 1989
PubMed
Summary
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Anorexia nervosa patients do not conserve energy at rest or during exercise despite malnutrition. Weight restoration does not alter resting energy expenditure per lean body mass or exercise energy use.

Area of Science:

  • Metabolism and Nutrition
  • Clinical Physiology

Background:

  • Anorexia nervosa is characterized by low energy intake and often hyperactivity.
  • Energy conservation strategies are expected in malnourished states.

Purpose of the Study:

  • To investigate energy expenditure at rest and during exercise in anorexia nervosa patients.
  • To determine if malnutrition induces energy sparing mechanisms.

Main Methods:

  • Measured resting energy expenditure (REE) and energy expenditure during moderate cycling exercise (30W, 6 min).
  • Assessed 11 adult anorectic patients before and after weight gain during treatment.

Main Results:

  • Resting energy expenditure was lower than predicted in malnourished patients.

Related Experiment Videos

  • REE increased after weight gain but remained unchanged per kg of lean body mass.
  • Total oxygen consumption during exercise was similar before and after refeeding.

    • Conclusions:

    • Weight loss and malnutrition in anorexia nervosa do not lead to energy economy at rest per lean body mass.
    • Moderate cycling exercise energy expenditure is not altered by malnutrition or refeeding in anorexia nervosa.