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Updated: May 5, 2026

Optimized Management of Endovascular Treatment for Acute Ischemic Stroke
Published on: January 18, 2018
Management of acute occlusion after percutaneous transluminal coronary angioplasty
1Division of Cardiovascular Diseases, Mayo Clinic, Rochester, Minnesota 55905.
Insights
Preventing acute coronary occlusion after angioplasty involves technical care and medications like heparin and aspirin. If occlusion occurs, strategies include re-angioplasty, stents, or bypass grafting.
Area of Science:
- Cardiology
- Interventional Cardiology
Background:
- Acute coronary occlusion is a recognized complication following angioplasty.
- Persistent occlusion can result in myocardial infarction and mortality.
Purpose of the Study:
- To outline strategies for preventing and managing acute coronary occlusion post-angioplasty.
- To discuss optimal interventions when prompt reopening is not feasible.
Main Methods:
- Review of established protocols for angioplasty complication management.
- Analysis of treatment options including prophylactic measures and interventional strategies.
Main Results:
- Prevention strategies include meticulous attention to technical factors and prophylactic heparin and aspirin.
- Management options for acute occlusion encompass re-angioplasty, perfusion balloons, stents, and atherectomy.
Conclusions:
- Prompt reopening of occluded arteries is crucial.
- Coronary artery bypass grafting is the recommended course of action when immediate reopening fails.
Abstract:
Acute coronary occlusion is a not infrequent complication of angioplasty. When it persists, it commonly leads to myocardial infarction, and sometimes to death. Ideally, it should be prevented by careful attention to technical predisposing factors and the routine prophylactic administration of heparin and aspirin. There are a number of strategies for managing the problem when it does occur; these frequently include re-angioplasty with standard or perfusion balloon catheters and the use of stents or atherectomy. However, if prompt reopening is not possible, then immediate coronary artery bypass grafting may be the wisest choice.
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