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Updated: Apr 5, 2026
Author Spotlight: Studying Clinical Characters and Epilepsy Outcomes After Frontal Disconnection in Patients with MOGHE
Published on: August 16, 2024
Pre-operative evaluation in pediatric patients with cortical dysplasia
Elia M Pestana Knight1, Jorge Gonzalez-Martinez2, Ajay Gupta2
1Epilepsy Center, Neurological Institute, Cleveland Clinic, 9500 Euclid Ave / S51, Cleveland, OH, 44195, USA. pestane@ccf.org.
Insights
Focal cortical dysplasia (FCD) causes difficult-to-treat epilepsy in children. Understanding age-specific features and non-invasive tools is key for successful epilepsy surgery selection.
Area of Science:
- Pediatric Neurology
- Epileptology
- Neurosurgery
Background:
- Focal cortical dysplasia (FCD) is a significant cause of intractable epilepsy in pediatric populations.
- It frequently necessitates epilepsy surgery for seizure control in infants and children.
Observation:
- Evaluating young children with FCD requires understanding unique age-related clinical characteristics.
- Non-invasive diagnostic tools play a crucial role in presurgical assessments.
Findings:
- Tailoring presurgical evaluation to age-specific features improves surgical candidacy selection for FCD.
- Integrating data from various non-invasive tools enhances the accuracy of the presurgical hypothesis.
Implications:
- Optimized presurgical evaluation can lead to better outcomes for children with FCD-related epilepsy.
- This approach aims to identify pediatric patients most likely to benefit from epilepsy surgery.
- Further research into age-specific FCD presentations and diagnostic tool efficacy is warranted.
Introduction:
Focal cortical dysplasia (FCD) is an important cause of refractory seizures and catastrophic epilepsy in infants and children who had epilepsy surgery.
Aims Of The Review:
This manuscript will discuss age-related unique clinical characteristics in evaluation of infants and young children because the understanding of these age-related features is critical in selecting children who can benefit from epilepsy surgery. In addition, we will review the non-invasive tools available for the presurgical evaluation of children with FCD and their individual contribution to the formulation of the presurgical hypothesis.
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