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Plasmonic Gold Decorated MWCNT Nanocomposite for Localized Plasmon Resonance Sensing
J Ozhikandathil1, S Badilescu1, M Packirisamy1
1Concordia University, Optical Bio-Microsystems Laboratory, Department of Mechanical and Industrial Engineering, Concordia University, Montreal, H3G 1M8, Canada.
Scientific Reports
|August 19, 2015
Summary
This study developed a novel biosensor using gold nanoparticles and Multi-Walled Carbon Nanotubes (MWCNT) for detecting bovine growth hormone. The hybrid platform significantly enhances detection sensitivity for this important agricultural biomarker.
Area of Science:
- Nanotechnology
- Biosensing
- Materials Science
Background:
- Carbon nanotubes and gold nanoparticles possess unique synergistic properties.
- Existing methods for detecting recombinant bovine growth hormone (rbST) lack sufficient sensitivity.
- Multi-Walled Carbon Nanotubes (MWCNT) can be modified to enhance optical responsiveness.
Purpose of the Study:
- To create a novel biosensor for detecting recombinant bovine growth hormone (rbST).
- To leverage the synergistic properties of MWCNT and gold nanoparticles for enhanced biosensing.
- To utilize Localized Surface Plasmon Resonance (LSPR) for sensitive detection.
Main Methods:
- Synthesized a gold-MWCNT composite by decorating MWCNT with gold nanoparticles.
- Fabricated the composite onto a glass substrate using a drop-casting method, forming a coffee ring pattern.
- Investigated the synthesis mechanism using Scanning Electron Microscopy under low-temperature vacuum conditions.
Main Results:
- Successfully synthesized a gold-MWCNT nanocomposite with gold nanoparticles concentrated along the coffee ring perimeter.
- Demonstrated the LSPR properties of the gold-MWCNT nanocomposite for plasmonic detection of rbST.
- Achieved a significantly improved sensitivity of 1 ng/ml for rbST detection, compared to 25 ng/ml with gold nanoparticles alone.
Conclusions:
- The gold-MWCNT hybrid platform offers superior sensitivity for rbST detection compared to gold nanoparticles alone.
- The LSPR properties of the composite are effectively utilized for sensitive biosensing applications.
- This nanotechnology-based approach presents a promising advancement in the detection of agricultural biomarkers.
