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Published on: May 9, 2021
Generalized seizures in a neural field model with bursting dynamics
X Zhao1,2,3,4, P A Robinson5,6,7,8
1School of Physics, The University of Sydney, Sydney, New South Wales, 2006, Australia. xzha6112@uni.sydney.edu.au.
Abstract:
The mechanisms underlying generalized seizures are explored with neural field theory. A corticothalamic neural field model that has accounted for multiple brain activity phenomena and states is used to explore changes leading to pathological seizure states. It is found that absence seizures arise from instabilities in the system and replicate experimental studies in numerous animal models and clinical studies.
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