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Updated: Apr 5, 2026

Th17 Inflammation Model of Oropharyngeal Candidiasis in Immunodeficient Mice
Published on: February 18, 2015
Primary immunodeficiency update: Part II. Syndromes associated with mucocutaneous candidiasis and noninfectious
Dominique C Pichard1, Alexandra F Freeman2, Edward W Cowen1
1National Institutes of Health, National Cancer Institute, Bethesda, Maryland.
Abstract:
Several primary immunodeficiencies (PIDs) have recently been described that confer an elevated risk of fungal infections and noninfectious cutaneous manifestations. In addition, immunologic advances have provided new insights into our understanding of the pathophysiology of fungal infections in established PIDs. We reviewed PIDs that present with an eczematous dermatitis in part I. In part II of this continuing medical education article we discuss updates on PIDs associated with fungal infections, their biologic basis in PIDs, and noninfectious cutaneous manifestations.
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