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Quality of life in children with celiac disease: A paediatric cross-sectional study

Chiara Biagetti1, Rosaria Gesuita2, Simona Gatti1

  • 1Department of Pediatrics, Università Politecnica delle Marche, Ancona, Italy.

Digestive and Liver Disease : Official Journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver
|August 19, 2015
PubMed

Insights

Children with celiac disease generally have good quality of life on a gluten-free diet. However, co-morbidities and dietary challenges can negatively impact their well-being.

Area of Science:

  • Pediatric gastroenterology
  • Child psychology
  • Dietary science

Background:

  • Limited research exists on factors affecting the quality of life for children with celiac disease adhering to a gluten-free diet.
  • Understanding these factors is crucial for improving patient outcomes.

Purpose of the Study:

  • To assess the psycho-physical well-being of children with celiac disease on a gluten-free diet.
  • To identify specific challenges impacting their quality of life.

Main Methods:

  • Cross-sectional study involving 76 celiac and 143 non-celiac children (aged 2-18).
  • Utilized the Pediatric Quality of Life Inventory Test and an open-ended questionnaire on social impact.
  • Statistical analysis included Wilcoxon rank-sum test and quantile regression.

Main Results:

  • No significant overall difference in quality of life scores between celiac and non-celiac children.
  • Gluten-free diet positively influenced quality of life in children with "intermediate" scores.
  • Lower quality of life scores correlated with higher reported diet difficulties and co-morbidities.

Conclusions:

  • Celiac children generally exhibit good quality of life compared to controls.
  • Co-morbidities and difficulties managing the gluten-free diet are key factors reducing quality of life in celiac children.
  • Targeted interventions addressing these specific challenges can further enhance well-being.
Abstract

Keywords:
ChildGluten-free dietHealth-related quality of life

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