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Published on: February 23, 2024
Predictors of Mortality Among Pediatric Burn Patients in East Africa
Khatiya I Chelidze1, Christopher C Lim, Robert N Peck
1From the *Weill Cornell Medical College, New York, New York; †Catholic University of Health and Allied Sciences, Mwanza, Tanzania; ‡New York Presbyterian Hospital; and §New York Presbyterian Hospital - Weill Cornell Medical College.
Insights
Pediatric burn patients in rural developing areas have a 7.1% mortality rate. Higher total body surface area burned and younger age were key predictors of mortality in this study.
Area of Science:
- Pediatric Burn Care
- Global Health Outcomes
- Resource-Limited Settings
Background:
- Outcomes for pediatric burn patients in resource-limited, rural areas of developing nations are poorly understood.
- Establishing an electronic registry is crucial for data collection in such settings.
Purpose of the Study:
- To determine overall mortality rates and identify predictors of mortality in pediatric burn patients treated in a rural, developing world setting.
- To analyze factors such as underweight status and body part burned in relation to mortality.
Main Methods:
- An electronic registry of pediatric burn patients admitted from March 2013 to June 2014 was analyzed.
- Data included age, gender, burn percentage (TBSA%), body part burned, and mortality.
- Univariable, multivariable logistic regression, and Kaplan-Meier curves were used to assess mortality predictors.
Main Results:
- The overall mortality rate was 7.1% (15/211 patients).
- The strongest predictors of mortality were higher %TBSA (OR=1.31) and younger age (OR=0.20).
- Underweight status and burn location were not independent predictors of mortality.
Conclusions:
- This study provides critical data on pediatric burn patient mortality in a rural, developing world context.
- Unintentional scalds in the home were the most common cause of burns.
- %TBSA and younger age are significant factors influencing survival, informing targeted interventions.
Abstract:
Little is known about the outcomes of pediatric burn patients in resource-limited and rural locations of the developing world. In March 2013, our pediatric burn unit existing in this setting established an electronic registry of all patients. The authors analyzed the registry to determine overall mortality rates and predictors of mortality, including that of underweight status and body part burned. The secure electronic database of all admissions was reviewed for age, gender, weight, burn percentage (TBSA%), body part burned, cause/place of injury, length of stay, underweight status, surgery performed, reason for discharge, and mortality. Univariable and multivariable logistic regression was used to determine the variables associated with mortality. Kaplan-Meier curves were also analyzed. A total of 211 cases (59.7% male) admitted from March 2013 to June 2014 were reviewed. The median age, %TBSA, and length of stay were 2.0 years (1.3-3.3), 8.0% (5.0-13.4), and 8.5 days (4-14). The overall mortality rate was 15/211 (7.1%). Most injuries were unintentional (93.8%) scalds (85.3%) occurring in the home (98.1%). Two factors were significantly associated with mortality in the final multivariable model: %TBSA (odds ratio = 1.31 for 1% increase in %TBSA; 95% confidence interval = 1.17-1.46) and younger age (odds ratio = 0.20; 0.07-0.63). This study characterizes mortality among patients at a pediatric burn unit serving a rural population in the developing world. The majority of pediatric burns were unintentional scalds occurring in the home. %TBSA and lower age were the strongest predictors of mortality. Burn location and underweight status were not independent predictors of mortality. Overall mortality was 7.1%. These data are applicable to improving outcomes for patients in this burn unit and similar settings of its kind.
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