Related Experiment Video

Updated: Apr 5, 2026

A High-Throughput Multiplexed Screening for Type 1 Diabetes, Celiac Diseases, and COVID-19
06:46

A High-Throughput Multiplexed Screening for Type 1 Diabetes, Celiac Diseases, and COVID-19

Published on: July 5, 2022

3.4K

Quality of Life and Psychological Screening in Children with Type 1 Diabetes and their Mothers

N S Duru1, M Civilibal1, M Elevli1

  • 1Department of Pediatrics Istanbul, Haseki Training and Research Hospital, Turkey.

Experimental and Clinical Endocrinology & Diabetes : Official Journal, German Society of Endocrinology [And] German Diabetes Association
|August 19, 2015
PubMed

Insights

Children with type 1 diabetes mellitus (T1DM) show higher depression. Their mothers experience reduced quality of life, increased depression, and anxiety, highlighting the need for mental health screening.

Area of Science:

  • Pediatrics
  • Endocrinology
  • Psychology

Background:

  • Type 1 diabetes mellitus (T1DM) is a chronic condition affecting children, potentially impacting their mental health and that of their families.
  • Maternal mental health and quality of life are crucial factors in managing childhood chronic illnesses.
  • Limited research exists on the combined mental health burden in children with T1DM and their mothers.

Purpose of the Study:

  • To assess depression levels in children diagnosed with T1DM.
  • To evaluate the quality of life, depression, and anxiety in mothers of children with T1DM.
  • To explore correlations between child and maternal mental health outcomes.

Main Methods:

  • Cross-sectional study comparing 30 children with T1DM and their mothers to 30 healthy children and their mothers.
  • Utilized Children's Depression Inventory (CDI) for children.
  • Administered SF-36, Beck Depression Inventory (BDI), and Spielberg's State-Trait Anxiety Inventory (STAI) to mothers.

Main Results:

  • Children with T1DM exhibited significantly higher depression scores (CDI) than controls.
  • Mothers of children with T1DM reported lower quality of life (SF-36) across most domains, higher depression (BDI), and anxiety (STAI).
  • Childhood depression (CDI) positively correlated with maternal depression (BDI) and negatively with maternal quality of life (SF-36 vitality and social functioning).

Conclusions:

  • Children with T1DM face a greater burden of depressive symptoms.
  • Mothers of children with T1DM experience significant psychological distress and diminished quality of life.
  • Integrated mental health screening for both children with T1DM and their mothers is recommended.

Related Concept Videos

Diabetes Mellitus: Type 2 and Gestational01:22

Diabetes Mellitus: Type 2 and Gestational

Type 2 diabetes, characterized by insulin resistance, arises when the insulin receptors on cells lose responsiveness to insulin, diminishing the cell's capacity to take up glucose, resulting in elevated blood glucose levels. To receive a diagnosis of Type 2 diabetes, a series of blood glucose tests are necessary to assess whether the blood glucose falls within normal parameters. If the result is out of the normal range, a patient may be diagnosed as prediabetic or diabetic, depending on the...
5.6K
Diabetes Mellitus: Overview and Type I Subtype01:22

Diabetes Mellitus: Overview and Type I Subtype

Diabetes mellitus is a chronic metabolic disorder characterized by high blood glucose levels due to inadequate insulin production, insulin resistance, or both. The condition affects millions worldwide and can significantly impact their health and quality of life.
Type 1 diabetes is an autoimmune disease in which the immune system mistakenly attacks and destroys the insulin-producing beta cells in the pancreas. As a result, the body is unable to produce sufficient insulin, and individuals with...
6.1K
Pathophysiology of Diabetes01:20

Pathophysiology of Diabetes

Diabetes mellitus is a chronic metabolic disorder characterized by hyperglycemia. The four categories of diabetes are type 1 diabetes, type 2 diabetes, other specific types of diabetes, and gestational diabetes.
Type 1 diabetes is characterized by autoimmune-mediated destruction of pancreatic β cells, with environmental factors potentially triggering this process in genetically susceptible individuals. Despite many not having a family history, certain genes increase susceptibility,...
4.5K
Diabetes: Symptoms, Diagnosis, and Complications01:15

Diabetes: Symptoms, Diagnosis, and Complications

For most patients, experiencing several weeks of polyuria, polydipsia, fatigue, and significant weight loss may indicate the presence of diabetes. Furthermore, adults displaying the phenotypic appearance of type 2 diabetes (particularly those who are obese and not initially insulin-requiring), may have islet cell autoantibodies, suggesting autoimmune-mediated β cell destruction and a diagnosis of latent autoimmune diabetes of adults (LADA). The categorization of glucose homeostasis is...
2.8K
Diabetes: Management and Pharmacotherapy01:15

Diabetes: Management and Pharmacotherapy

The therapy for diabetes aims to alleviate hyperglycemia-related symptoms, prevent acute metabolic decompensation, and reduce chronic end-organ complications. Glycemic control is evaluated through short-term (self-monitoring, continuous glucose monitoring) and long-term (A1c, fructosamine) metrics, enabling near real-time tracking of blood glucose levels and reflecting glycemic control over specific time frames.
Insulin remains the cornerstone of treatment for most patients with type 1 and many...
1.5K
Insulin: Dosing Regimen and Adverse Effects01:16

Insulin: Dosing Regimen and Adverse Effects

Insulin-replacement therapy usually includes both long-acting insulin (basal) and short-acting insulin (to cater to postprandial needs). In a diverse group of type 1 diabetes patients, the average daily insulin dose is typically 0.5-0.7 units/kg body weight. However, obese patients and pubertal adolescents may need more due to insulin resistance.
The basal dose constitutes about 40%-50% of the total daily dose, with the rest as premeal insulin. The mealtime insulin dose should mirror...
1.2K