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B-cells in systemic sclerosis: emerging evidence from genetics to phenotypes

Minghua Wu1, Chandra Mohan

  • 1aDivision of Rheumatology & Clinical Immunogenetics, The University of Texas Health Science Center at Houston bDepartment of Biomedical Engineering, University of Houston, Houston, Texas, USA *Both Minghua Wu and Chandra Mohan contributed equally to this work.

Current Opinion in Rheumatology
|August 19, 2015
PubMed
Summary

B-cells are pivotal in systemic sclerosis (SSc) pathogenesis, influencing fibroblast activity and disease progression. Evidence shows B-cell alterations and successful anti-CD20 therapy in SSc patients.

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