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Updated: Apr 5, 2026

The bm12 Inducible Model of Systemic Lupus Erythematosus SLE in C57BL/6 Mice
Published on: November 1, 2015
[Overcoming disease in systemic lupus erythematosus]
1Universitätsklinikum Düsseldorf, Moorenstr. 5, 40225, Düsseldorf, Deutschland, schneiderm@med.uni-duesseldorf.de.
Background:
Systemic lupus erythematosus (SLE) is a chronic inflammatory autoimmune disease affecting a broad range of different organ systems and, hence, presenting with multiple symptomatic domains, which considerably reduces the quality of life of patients. Within the last decade the prognosis of the disease has been significantly improved by novel therapies and intensive monitoring; however, non-pharmaceutical strategies for symptom control, self-efficacy and coping abilities for those affected are still insufficiently established.
Objective:
This article describes the possibilities and limitations of non-pharmaceutical strategies and makes suggestions for future treatment and research.
Results:
Preliminary interventional studies using psychoeducational, psychosocial and behavioral psychotherapeutic approaches, have consistently shown that the needs and expectations of patients related to help and support by doctors and professional care can be adequately and sustainably met. In addition, coping abilities and the quality of life can be increased.
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