[The beneficial and harmful interactions of antihypertensive drugs]

Drug interaction has been a very important and serious aspect of the modern management of hypertension. The constantly rising number of antihypertensive drugs has been contributing to the number of pharmacological interactions during antihypertensive treatment. Some of the interactions are very helpful and favourable leading to the synergistic effects of the drugs, while others are undesirable and useless, diminishing the antihypertensive effects of individual drugs, or transforming the effects and causing serious and harmful side effects. If a patient, suffering from hypertension, is treated for another associated disease, the number of interactions is increasing. If the nature of the interactions is not know and if they are ignored, the treatment can be more harmful then beneficial.