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Eco-Friendly Synthesis of a New Class of Pyridinium-Based Ionic Liquids with Attractive Antimicrobial Activity
1Department of Chemistry, Taibah University, Al-Madina Al-Mounawara 30002, Saudi Arabia. mouslim@mail.be.
Abstract:
The present study reports a green synthesis of a new family of ionic liquids (ILs) based on functionalized 4-dimethylaminopyridinium derivatives. The structures of 23 newly synthesized ILs (2-24) were confirmed by FT-IR, (1)H-, (13)C-, (11)B-, (19)F-, and (31)P-NMR spectroscopy and mass spectrometry. The antimicrobial activity of all novel ILs was tested against a panel of bacteria and fungi. The results prove that all tested ILs are effective antibacterial and antifungal agents, especially 4-(dimethylamino)-1-(4-phenoxybutyl) pyridinium derivatives 5 and 19.
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