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ILC Lineage Specification: To Be or Not 11b, That Is the Question
Tomasz Kostrzewski1, Hugh J M Brady1
1Department of Life Sciences, Imperial College, London SW7 2AZ, UK.
Immunity
|August 20, 2015
Abstract
None:
The transcription factor Bcl11b is important for T cell development and maintaining their phenotype. In this issue of Immunity, Califano et al. (2015) show that Bcl11b has a role in specifying type II innate lymphoid cell (ILC2) identity and blocks their conversion to ILC3s.
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